Inflammation must be tightly regulated to both defend against pathogens and restore tissue
homeostasis. The resolution of inflammatory responses is a dynamic process orchestrated …

Biologists, physicians and immunologists have contributed to the understanding of the
cellular participants and biological pathways involved in inflammation. Here, we provide a …

Over the past several decades, much has been revealed about the nature of the host innate
immune response to microorganisms, with the identification of pattern recognition receptors …

Intravascular hemolysis, or the destruction of red blood cells in the circulation, can occur in
numerous diseases, including the acquired hemolytic anemias, sickle cell disease and β …

Review on how traumatic injuries influence immune system phenotypes and functions.
Traumatic injuries induce a complex host response that disrupts immune system …

A full innate immune system (eg complement system, scavenger receptors, Toll-like
receptors (TLR)) has been described in the CNS and is thought to be an extremely efficient …

Sepsis is characterized by a dysregulated immune response to infections that causes life-
threatening organ dysfunction and even death. When infections occur, bacterial cell wall …

The resolution of inflammation is central to the maintenance of good health and immune
homeostasis. Recently, several intracellular stress proteins have been described as having …

Inflammation has evolved as a protective response to insult or injury, it's a primordial
response that eliminates or neutralises foreign organisms or material, the resolution of …

Neutrophils are the most abundant innate immune cell and are equipped with highly
destructive molecular cargo. As such, these cells were long thought to be short-lived killer …