Cell death is a vital process that occurs in billions of cells in the human body every day. This
process helps maintain tissue homeostasis, supports recovery from acute injury, deals with …

Damage-associated molecular pattern molecules (DAMPs) are endogenous molecules that
are constitutively expressed and released upon tissue damage, resulting in activation of the …

Macrophages are dynamic cells that play critical roles in the induction and resolution of
sterile inflammation. In this review, we will compile and interpret recent findings on the …

Damage-associated molecular patterns (DAMPs) are danger signals (or alarmins) alerting
immune cells through pattern recognition receptors (PRRs) to begin defense activity …

Inflammatory mediators play important roles in the development and progression of cancer.
Cellular stress, damage, inflammation, and necrotic cell death cause release of endogenous …

Damage-associated molecular patterns (DAMPs) are molecules that can be actively or
passively released by injured tissues and that activate the immune system. Here we show …

Neutrophils are an absolutely essential part of the innate immune system, playing an
essential role in the control of infectious diseases but more recently are also being viewed …

Inflammation is an essential immune response that enables survival during infection or
injury and maintains tissue homeostasis under a variety of noxious conditions. Inflammation …

Activation of Toll-like receptor (TLR) signaling and related pathways by microbial products
drives inflammatory responses, host-defense pathways and adaptive immunity. The cost of …

Innate and adaptive immune systems consist of cells and molecules that work together in
concert to fight against microbial infection and maintain homeostasis. Hosts encounter …