The landscape of human STR variation
Short tandem repeats are among the most polymorphic loci in the human genome. These
loci play a role in the etiology of a range of genetic diseases and have been frequently …
loci play a role in the etiology of a range of genetic diseases and have been frequently …
Genome-wide profiling of heritable and de novo STR variations
T Willems, D Zielinski, J Yuan, A Gordon, M Gymrek… - Nature …, 2017 - nature.com
Short tandem repeats (STRs) are highly variable elements that play a pivotal role in multiple
genetic diseases, population genetics applications, and forensic casework. However, it has …
genetic diseases, population genetics applications, and forensic casework. However, it has …
Characterization of genome-wide STR variation in 6487 human genomes
Y Shi, Y Niu, P Zhang, H Luo, S Liu, S Zhang… - Nature …, 2023 - nature.com
Short tandem repeats (STRs) are abundant and highly mutagenic in the human genome.
Many STR loci have been associated with a range of human genetic disorders. However …
Many STR loci have been associated with a range of human genetic disorders. However …
Sequencing and characterizing short tandem repeats in the human genome
HA Tanudisastro, IW Deveson, H Dashnow… - Nature Reviews …, 2024 - nature.com
Short tandem repeats (STRs) are highly polymorphic sequences throughout the human
genome that are composed of repeated copies of a 1–6-bp motif. Over 1 million variable …
genome that are composed of repeated copies of a 1–6-bp motif. Over 1 million variable …
STRSeq: A catalog of sequence diversity at human identification Short Tandem Repeat loci
KB Gettings, LA Borsuk, D Ballard, M Bodner… - Forensic Science …, 2017 - Elsevier
Abstract The STR Sequencing Project (STRSeq) was initiated to facilitate the description of
sequence-based alleles at the Short Tandem Repeat (STR) loci targeted in human …
sequence-based alleles at the Short Tandem Repeat (STR) loci targeted in human …
Profiling of short-tandem-repeat disease alleles in 12,632 human whole genomes
Short tandem repeats (STRs) are hyper-mutable sequences in the human genome. They are
often used in forensics and population genetics and are also the underlying cause of many …
often used in forensics and population genetics and are also the underlying cause of many …
Population-scale sequencing data enable precise estimates of Y-STR mutation rates
Short tandem repeats (STRs) are mutation-prone loci that span nearly 1% of the human
genome. Previous studies have estimated the mutation rates of highly polymorphic STRs by …
genome. Previous studies have estimated the mutation rates of highly polymorphic STRs by …
Accurate typing of short tandem repeats from genome-wide sequencing data and its applications
Short tandem repeats (STRs) are implicated in dozens of human genetic diseases and
contribute significantly to genome variation and instability. Yet profiling STRs from short-read …
contribute significantly to genome variation and instability. Yet profiling STRs from short-read …
A genomic view of short tandem repeats
M Gymrek - Current opinion in genetics & development, 2017 - Elsevier
Short tandem repeats (STRs) are some of the fastest mutating loci in the genome. Tools for
accurately profiling STRs from high-throughput sequencing data have enabled genome …
accurately profiling STRs from high-throughput sequencing data have enabled genome …
lobSTR: a short tandem repeat profiler for personal genomes
Short tandem repeats (STRs) have a wide range of applications, including medical genetics,
forensics, and genetic genealogy. High-throughput sequencing (HTS) has the potential to …
forensics, and genetic genealogy. High-throughput sequencing (HTS) has the potential to …