The development of the microbiome from infancy to childhood is dependent on a range of
factors, with microbial–immune crosstalk during this time thought to be involved in the …

Abstract Type 1 diabetes (T1D) is an autoimmune disease that targets pancreatic islet beta
cells and incorporates genetic and environmental factors, including complex genetic …

Immediately after birth, newborn babies experience rapid colonization by microorganisms
from their mothers and the surrounding environment. Diseases in childhood and later in life …

The human gut microbiome matures towards the adult composition during the first years of
life and is implicated in early immune development. Here, we investigate the effects of …

The gut microbiome is associated with diverse diseases,–, but a universal signature of a
healthy or unhealthy microbiome has not been identified, and there is a need to understand …

Commensal gut bacterial communities (microbiomes) are predicted to influence human
health and disease,. Neonatal gut microbiomes are colonized with maternal and …

The gut microbiota of preterm infants develops predictably,,,,,–, with pioneer species
colonizing the gut after birth, followed by an ordered succession of microorganisms. The gut …

Immunoglobulin A (IgA), the major class of antibody secreted by the gut mucosa, is an
important contributor to gut barrier function,,. The repertoire of IgA bound to gut bacteria …

Our knowledge of species and functional composition of the human gut microbiome is
rapidly increasing, but it is still based on very few cohorts and little is known about variation …

Human microbiota assembly commences at birth, seeded by both maternal and
environmental microorganisms. Ecological theory postulates that primary colonizers dictate …