Oxidative stress is one of the earliest events of Alzheimer disease (AD), with implications as
an important mediator in the onset, progression and pathogenesis of the disease. The …

Oxidative stress is a striking feature of susceptible neurons in the Alzheimer's disease brain.
Importantly, because oxidative stress is an early event in Alzheimer's disease, proximal to …

Multiple lines of evidence demonstrate that oxidative stress is an early event in Alzheimer's
disease (AD), occurring prior to cytopathology, and therefore may play a key pathogenic role …

Alzheimer's disease (AD) is a devastating neurodegenerative disorder without a cure. Most
AD cases are sporadic where age represents the greatest risk factor. Lack of understanding …

Alzheimer's disease (AD) is the most common neurodegenerative disease characterized by
the presence of senile plaques (SPs) and neurofibrillary tangles (NFTs) in the hippocampus …

Oxidative stress is typically reported in neurodegenerative diseases. Although the
mechanisms underlying this condition are not completely understood, the brain appears …

Although the basis of Alzheimer's disease (AD) etiology remains unknown, oxidative stress
(OS) has been recognized as a prodromal factor associated to its progression. OS refers to …

Alzheimer's disease (AD) is the most common cause of dementia and a progressive
neurodegeneration that appears to result from multiple pathogenic mechanisms (including …

Increasing numbers of individuals, particularly the elderly, suffer from neurodegenerative
disorders. These diseases are normally characterized by progressive loss of neuron cells …

Alzheimer′ s disease (AD) is the most common cause of dementia in the elderly, affecting
several million of people worldwide. Pathological changes in the AD brain include the …