Heterogeneity among isolates reveals that fitness in low oxygen correlates with Aspergillus fumigatus virulence

CH Kowalski, SR Beattie, KK Fuller, EA McGurk… - MBio, 2016 - Am Soc Microbiol
Previous work has shown that environmental and clinical isolates of Aspergillus fumigatus
represent a diverse population that occupies a variety of niches, has extensive genetic …

Heterogeneity confounds establishment of “a” model microbial strain

NP Keller - MBio, 2017 - Am Soc Microbiol
Aspergillus fumigatus is a ubiquitous environmental mold and the leading cause of diverse
human diseases ranging from allergenic bronchopulmonary aspergillosis (ABPA) to …

Interleukin 1α is critical for resistance against highly virulent Aspergillus fumigatus isolates

AK Caffrey-Carr, CH Kowalski, SR Beattie… - Infection and …, 2017 - Am Soc Microbiol
Heterogeneity among Aspergillus fumigatus isolates results in unique virulence potential
and inflammatory responses. How these isolates drive specific immune responses and how …

Isolate-Dependent Growth, Virulence, and Cell Wall Composition in the Human Pathogen Aspergillus fumigatus

N Amarsaikhan, EM O'Dea, A Tsoggerel, H Owegi… - PloS one, 2014 - journals.plos.org
The ubiquitous fungal pathogen Aspergillus fumigatus is a mediator of allergic sensitization
and invasive disease in susceptible individuals. The significant genetic and phenotypic …

Pathogenicity and virulence of Aspergillus fumigatus

K Earle, C Valero, DP Conn, G Vere, PC Cook… - Virulence, 2023 - Taylor & Francis
Pulmonary infections caused by the mould pathogen Aspergillus fumigatus are a major
cause of morbidity and mortality globally. Compromised lung defences arising from …

Aspergillus fumigatus morphology and dynamic host interactions

FL Van De Veerdonk, MS Gresnigt, L Romani… - Nature Reviews …, 2017 - nature.com
Aspergillus fumigatus is an environmental filamentous fungus that can cause life-threatening
disease in immunocompromised individuals. The interactions between A. fumigatus and the …

The pathobiology of Aspergillus fumigatus

JP Latgé - Trends in microbiology, 2001 - cell.com
Aspergillus fumigatus is the most prevalent airborne fungal pathogen in developed
countries, and in immunocompromised patients causes a usually fatal invasive aspergillosis …

Pathogenesis of Aspergillus fumigatus in Invasive Aspergillosis

TRT Dagenais, NP Keller - Clinical microbiology reviews, 2009 - Am Soc Microbiol
Aspergillus species are globally ubiquitous saprophytes found in a variety of ecological
niches. Almost 200 species of aspergilli have been identified, less than 20 of which are …

Aspergillus fumigatus, a saprotrophic pathogenic fungus

JP Latge - Mycologist, 2003 - Elsevier
Aspergillus fumigatus is the most common and life-threatening aerial fungal pathogen,
especially among immuno-compromised hosts. Understanding the pathobiology of this …

Aspergillus fumigatus metabolism: Clues to mechanisms of in vivo fungal growth and virulence

SD Willger, N Grahl, SD Willger, N Grahl… - Medical …, 2009 - Taylor & Francis
Aspergillus fumigatus is a saprophytic fungus commonly found in soil and compost piles. In
immunocompromised patients it takes on a sinister form as a potentially lethal opportunistic …