Will precision medicine improve population health?

MJ Khoury, S Galea - Jama, 2016 - jamanetwork.com
Announcementof the precision medicine initiative has led to a variety of responses, ranging
from enthusiastic expectations1 to explicit skepticism, 2 about potential health benefits …

The precision medicine initiative: a new national effort

EA Ashley - Jama, 2015 - jamanetwork.com
The announcement by President Obama of a precision medicine initiative created
excitement in the medical community. The president referred not to personalized medicine …

A public health perspective on a national precision medicine cohort: balancing long-term knowledge generation with early health benefit

MJ Khoury, JP Evans - Jama, 2015 - jamanetwork.com
The new US precision medicine initiative1 has been made possible by improvement and
price reduction in genome sequencing, as well as advances in multiple sectors of …

Comparison of 2 treatment models: precision medicine and preventive medicine

BM Psaty, OM Dekkers, RS Cooper - Jama, 2018 - jamanetwork.com
In an effort to improvethe risk-benefit profile of therapies in clinical care, precision medicine
seeks to identify and make use of factors, often genetic variants or biomarkers, that influence …

Realizing the full potential of precision medicine in health and health care

VJ Dzau, GS Ginsburg - Jama, 2016 - jamanetwork.com
Precisionmedicinehasthepotentialtotransfor…-cine by tailoring treatments to individuals. By
providingtherighttreatmentattherighttime, healthcarecould be delivered with greater …

Precision medicine from a public health perspective

R Ramaswami, R Bayer, S Galea - Annual Review of Public …, 2018 - annualreviews.org
Over the past decade, precision medicine (PM) approaches have received significant
investment to create new therapies, learn more about disease processes, and potentially …

[HTML][HTML] Precision public health for the era of precision medicine

MJ Khoury, MF Iademarco, WT Riley - American journal of …, 2016 - ncbi.nlm.nih.gov
The Precision Medicine Initiative1 promises a new healthcare era. A proposed 1 million—
person cohort could create a deeper understanding of disease causation. Improvements in …

Public health in the precision-medicine era

R Bayer, S Galea - New England Journal of Medicine, 2015 - Mass Medical Soc
Public Health in the Precision-Medicine Era | New England Journal of Medicine Skip to main
content Access provided byUT MD ANDERSON CANCER CENTER The New England Journal …

Seven questions for personalized medicine

MJ Joyner, N Paneth - Jama, 2015 - jamanetwork.com
Personalized or precision medicine maintains that medical care and public health will be
radically transformed by prevention and treatment programs more closely targeted to the …

Promises, promises, and precision medicine

MJ Joyner, N Paneth - The Journal of clinical investigation, 2019 - Am Soc Clin Investig
In 1999 Francis Collins published a foundational document of precision medicine entitled
“Medical and Societal Consequences of the Human Genome Project,”(1) which made …