Abundance and length of simple repeats in vertebrate genomes are determined by their structural properties

A Bacolla, JE Larson, JR Collins, J Li… - Genome …, 2008 - genome.cshlp.org
Microsatellites are abundant in vertebrate genomes, but their sequence representation and
length distributions vary greatly within each family of repeats (eg, tetranucleotides) …

Every microsatellite is different: Intrinsic DNA features dictate mutagenesis of common microsatellites present in the human genome

KA Eckert, SE Hile - … in cooperation with the University of Texas …, 2009 - Wiley Online Library
Microsatellite sequences are ubiquitous in the human genome and are important regulators
of genome function. Here, we examine the mutational mechanisms governing the stability of …

A matter of life or death: how microsatellites emerge in and vanish from the human genome

YD Kelkar, KA Eckert, F Chiaromonte… - Genome …, 2011 - genome.cshlp.org
Microsatellites—tandem repeats of short DNA motifs—are abundant in the human genome
and have high mutation rates. While microsatellite instability is implicated in numerous …

Global microsatellite content distinguishes humans, primates, animals, and plants

CL Galindo, LJ McIver, JF McCormick… - Molecular biology …, 2009 - academic.oup.com
Microsatellites are highly mutable, repetitive sequences commonly used as genetic markers,
but they have never been studied en masse. Using a custom microarray to measure …

Exploiting dinucleotide microsatellites conserved among mammalian species

HS Sun, BW Kirkpatrick - Mammalian Genome, 1996 - Springer
Dinucleotide microsatellites are useful for gene mapping projects. Depending upon
definition of conservation, published estimates of dinucleotide microsatellite conservation …

A genomic portrait of human microsatellite variation

BA Payseur, P Jing, RJ Haasl - Molecular biology and evolution, 2011 - academic.oup.com
Rapid advances in DNA sequencing and genotyping technologies are beginning to reveal
the scope and pattern of human genomic variation. Although single nucleotide …

Microsatellites in different eukaryotic genomes: survey and analysis

G Tóth, Z Gáspári, J Jurka - Genome research, 2000 - genome.cshlp.org
We examined the abundance of microsatellites with repeated unit lengths of 1–6 base pairs
in several eukaryotic taxonomic groups: primates, rodents, other mammals, nonmammalian …

A relationship between lengths of microsatellites and nearby substitution rates in mammalian genomes

MF Santibáñez-Koref, R Gangeswaran… - … Biology and Evolution, 2001 - academic.oup.com
A number of studies have indicated an influence of sequences flanking tandem repeats on
repeat stability (Monckton et al. 1994; Shimizu et al. 1996; Bowater et al. 1997; Jeffreys …

Microsatellite evolution inferred from human–chimpanzee genomic sequence alignments

MT Webster, NGC Smith… - Proceedings of the …, 2002 - National Acad Sciences
Most studies of microsatellite evolution utilize long, highly mutable loci, which are
unrepresentative of the majority of simple repeats in the human genome. Here we use an …

Two distinct modes of microsatellite mutation processes: evidence from the complete genomic sequences of nine species

D Dieringer, C Schlötterer - Genome research, 2003 - genome.cshlp.org
We surveyed microsatellite distribution in 10 completely sequenced genomes. Using a
permutation-based statistic, we assessed for all 10 genomes whether the microsatellite …