Abundance and length of simple repeats in vertebrate genomes are determined by their structural properties
Microsatellites are abundant in vertebrate genomes, but their sequence representation and
length distributions vary greatly within each family of repeats (eg, tetranucleotides) …
length distributions vary greatly within each family of repeats (eg, tetranucleotides) …
Every microsatellite is different: Intrinsic DNA features dictate mutagenesis of common microsatellites present in the human genome
KA Eckert, SE Hile - … in cooperation with the University of Texas …, 2009 - Wiley Online Library
Microsatellite sequences are ubiquitous in the human genome and are important regulators
of genome function. Here, we examine the mutational mechanisms governing the stability of …
of genome function. Here, we examine the mutational mechanisms governing the stability of …
A matter of life or death: how microsatellites emerge in and vanish from the human genome
YD Kelkar, KA Eckert, F Chiaromonte… - Genome …, 2011 - genome.cshlp.org
Microsatellites—tandem repeats of short DNA motifs—are abundant in the human genome
and have high mutation rates. While microsatellite instability is implicated in numerous …
and have high mutation rates. While microsatellite instability is implicated in numerous …
Global microsatellite content distinguishes humans, primates, animals, and plants
CL Galindo, LJ McIver, JF McCormick… - Molecular biology …, 2009 - academic.oup.com
Microsatellites are highly mutable, repetitive sequences commonly used as genetic markers,
but they have never been studied en masse. Using a custom microarray to measure …
but they have never been studied en masse. Using a custom microarray to measure …
Exploiting dinucleotide microsatellites conserved among mammalian species
HS Sun, BW Kirkpatrick - Mammalian Genome, 1996 - Springer
Dinucleotide microsatellites are useful for gene mapping projects. Depending upon
definition of conservation, published estimates of dinucleotide microsatellite conservation …
definition of conservation, published estimates of dinucleotide microsatellite conservation …
A genomic portrait of human microsatellite variation
BA Payseur, P Jing, RJ Haasl - Molecular biology and evolution, 2011 - academic.oup.com
Rapid advances in DNA sequencing and genotyping technologies are beginning to reveal
the scope and pattern of human genomic variation. Although single nucleotide …
the scope and pattern of human genomic variation. Although single nucleotide …
Microsatellites in different eukaryotic genomes: survey and analysis
We examined the abundance of microsatellites with repeated unit lengths of 1–6 base pairs
in several eukaryotic taxonomic groups: primates, rodents, other mammals, nonmammalian …
in several eukaryotic taxonomic groups: primates, rodents, other mammals, nonmammalian …
A relationship between lengths of microsatellites and nearby substitution rates in mammalian genomes
MF Santibáñez-Koref, R Gangeswaran… - … Biology and Evolution, 2001 - academic.oup.com
A number of studies have indicated an influence of sequences flanking tandem repeats on
repeat stability (Monckton et al. 1994; Shimizu et al. 1996; Bowater et al. 1997; Jeffreys …
repeat stability (Monckton et al. 1994; Shimizu et al. 1996; Bowater et al. 1997; Jeffreys …
Microsatellite evolution inferred from human–chimpanzee genomic sequence alignments
MT Webster, NGC Smith… - Proceedings of the …, 2002 - National Acad Sciences
Most studies of microsatellite evolution utilize long, highly mutable loci, which are
unrepresentative of the majority of simple repeats in the human genome. Here we use an …
unrepresentative of the majority of simple repeats in the human genome. Here we use an …
Two distinct modes of microsatellite mutation processes: evidence from the complete genomic sequences of nine species
D Dieringer, C Schlötterer - Genome research, 2003 - genome.cshlp.org
We surveyed microsatellite distribution in 10 completely sequenced genomes. Using a
permutation-based statistic, we assessed for all 10 genomes whether the microsatellite …
permutation-based statistic, we assessed for all 10 genomes whether the microsatellite …