Microsatellites and its application

Z Yun-Wu, Z Ya-Ping, OA RYDER - Zoological Research, 2001 - zoores.ac.cn
Microsatellites are tandem repeats of short nucleotide motifs (1-5 bp long) dispersing widely
and relatively evenly in eukaryotic genomes. The high degree of allelic diversity at each …

Microsatellites in the eukaryotic DNA mismatch repair genes as modulators of evolutionary mutation rate

DK Chang, D Metzgar, C Wills, CR Boland - Genome Research, 2001 - genome.cshlp.org
DNA mismatch repair (MMR) system—MSH3, MSH6, PMS2, and the recently discovered
MLH3—contain mononucleotide microsatellites in their coding sequences. This intriguing …

Ascertainment bias cannot entirely account for human microsatellites being longer than their chimpanzee homologues

G Cooper, DC Rubinsztein… - Human Molecular …, 1998 - academic.oup.com
A large majority of human microsatellite markers are longer than their homologues in
chimpanzees, suggesting that more expansion mutations have occurred in the lineage …

Microsatellites and other simple sequences: genomic context and mutational mechanisms

JM Hancock - Microsatellites: Evolution and applications, 1999 - cir.nii.ac.jp
抄録< jats: title> Abstract</jats: title>< jats: p>'Microsatellite'is now the commonest term used
to describe tandem repeats of short sequence motifs (no more than six bases long) …

Selection against frameshift mutations limits microsatellite expansion in coding DNA

D Metzgar, J Bytof, C Wills - Genome research, 2000 - genome.cshlp.org
Microsatellite enrichment is an excess of repetitive sequences characteristic to all studied
eukaryotes. It is thought to result from the accumulated effects of replication slippage …

Measuring microsatellite conservation in mammalian evolution with a phylogenetic birth–death model

SM Sawaya, D Lennon, E Buschiazzo… - Genome biology and …, 2012 - academic.oup.com
Microsatellites make up∼ 3% of the human genome, and there is increasing evidence that
some microsatellites can have important functions and can be conserved by selection. To …

Population-scale analysis of human microsatellites reveals novel sources of exonic variation

LJ McIver, JF McCormick, A Martin, JW Fondon III… - Gene, 2013 - Elsevier
Using our microsatellite specific genotyping method, we analyzed tandem repeats, which
are known to be highly variable with some recognized as biomarkers causative of disease …

Evolution of coding microsatellites in primate genomes

E Loire, D Higuet, P Netter… - Genome Biology and …, 2013 - academic.oup.com
Microsatellites (SSRs) are highly susceptible to expansions and contractions. When located
in a coding sequence, the insertion or the deletion of a single unit for a mono-, di-, tetra-, or …

Microsatellites within genes: structure, function, and evolution

YC Li, AB Korol, T Fahima, E Nevo - Molecular biology and …, 2004 - academic.oup.com
Recently, increasingly more microsatellites, or simple sequence repeats (SSRs) have been
found and characterized within protein-coding genes and their untranslated regions (UTRs) …

MSDB: a comprehensive, annotated database of microsatellites

AK Avvaru, D Sharma, A Verma, RK Mishra… - Nucleic acids …, 2020 - academic.oup.com
Microsatellites are short tandem repeats of 1–6 nucleotide motifs, studied for their utility as
genome markers and in forensics. Recent evidence points to the role of microsatellites in …