The capacity of cancer cells for abnormal growth and metastasis has made it difficult to find a
cure for tumor. Both males and females suffer from lung tumors, and physicians still deem …

The Wnt signaling pathway regulates cell proliferation, differentiation, migration, genetic
stability, and apoptosis in almost all tissues and organs. It plays a crucial role in the normal …

Lung cancer is currently the leading cause of cancer mortality and morbidity worldwide and
greatly burdens humanity. Therefore, the prevention and treatment of lung cancer remains a …

Wnt signal is known to play a significant role in many cellular processes such as cell
proliferation, survival, self-renewal, and differentiation. This pathway has been linked to …

Wnt signaling has recently emerged as a critical pathway in lung carcinogenesis as already
demonstrated in many cancers and particularly in colorectal cancer. We critically discuss in …

ABSTRACT Introduction: Wingless-type (Wnt) signaling is tightly regulated at multiple
cellular levels and is dysregulated in lung cancer. Therefore, it offers therapeutic targets for …

Cancer cell plasticity includes their interconversion into various subtypes or entirely different
cells through transdifferentiation. This allows the cells to survive in difficult …

Non-small cell lung cancer (NSCLC) is the malignant tumor with the highest morbidity and
leading cause of death worldwide, whereas its pathogenesis has not been fully elucidated …

Since the initial discovery of the oncogenic activity of WNT ligands our understanding of the
complex roles for WNT signaling pathways in lung cancers has increased substantially. In …

The Wnt pathway plays an important role in development and in regulating adult stem cell
systems. A variety of cellular processes are mediated by Wnt signaling, including …