Objective: To determine the incidence of Wnt pathway activation in patients with stage I
NSCLC and its influence on lung cancer recurrence. Background: Despite resection, the 5 …

Wnt signaling is involved in a large set of cellular and developmental processes, and when
mis-regulated can lead to both degenerative diseases and many types of cancer. The …

Wnt signaling was initially recognized to be vital for tissue development and homeostasis
maintenance. Further studies revealed that this pathway is also important for tumorigenesis …

Wnt signaling involves many aspects of development, cell biology and physiology. Mutations
in the Wnt gene can lead to abnormal embryonic development and cancer formation …

Background Previous study has confirmed that the occurrence of Wnt pathway activation is
associated with risk of non-small-cell lung cancer recurrence. However, whether the …

Wnt/β-catenin-mediated signaling is a key pathway regulating tissue growth and
development, and tumorigenesis, and has received increasing attention in recent years. In …

The Wnt/β-catenin signaling pathway plays a crucial role in various physiological processes,
encompassing development, tissue homeostasis, and cell proliferation. Under normal …

Background Wingless-type protein (Wnt) signaling pathway plays a crucial role in the
development of human malignancies, such as epithelial-to-mesenchymal transition (EMT) …

Purpose We aimed to examine the expression levels of the genes encoding adenomatous
polyposis coli (APC) 1, APC-2, Dickkopf related protein (DKK)-1, DKK-3, secreted frizzled …

WNT signaling presents an attractive target for cancer therapy due to its widespread
oncogenic role. However, the molecular players involved in WNT signaling and the impact of …