Objective. To review recent data on the aetiology of cleft lip and palate. Data sources.
MEDLINE literature search (1986-2003). Study selection. Literature and data on aetiology of …

Cleft lip and palate (CLP) are birth defects that affect the upper lip and the roof of the mouth.
CLP has a multifactorial etiology, comprising both genetic and environmental factors. In this …

Cleft lip with or without cleft palate is the most common facial birth defect and it is caused by
a complex interaction between genetic and environmental factors. The purpose of this …

Orofacial clefts (cleft lip, cleft palate) are among the most common of all major birth defects,
but very little is known about their causation. Genetic factors are thought to play a major role …

Orofacial clefts (OFCs) rank as the second most common congenital birth defect in the
United States after Down syndrome and are the most common head and neck congenital …

Objective The members of the International Consortium for Oral Clefts Genetics recognize
the need for collaboration between researchers involved in etiologic studies of …

Nonsyndromic cleft lip and/or palate (or orofacial cleft, OFC) is a malformation characterized
by an incomplete separation between nasal and oral cavities without any associated …

Cleft lip with or without cleft palate is one of the most common congenital malformations.
Epidemiology differentiates between cleft malformations connected with syndromes and the …

Cleft lip and palate are common congenital anomalies with significant medical,
psychological, social, and economic ramifications, affecting one in seven hundred live births …

Orofacial clefts include cleft lip (CL), cleft palate (CP), and cleft lip and palate (CLP), which
combined represent the largest group of craniofacial malformations in humans with an …