Decreased core crystallinity facilitated drug loading in polymeric micelles without affecting their biological performances

J Gou, S Feng, H Xu, G Fang, Y Chao, Y Zhang… - …, 2015 - ACS Publications
Cargo-loading capacity of polymeric micelles could be improved by reducing the core
crystallinity and the improvement in the amount of loaded cargo was cargo-polymer affinity …

Self-assembled methoxy poly (ethylene glycol)-cholesterol micelles for hydrophobic drug delivery

Y Yu, Y He, B Xu, Z He, Y Zhang, Y Chen… - Journal of …, 2013 - Elsevier
To promote the application of methoxy poly (ethylene glycol)-cholesterol (mPEG—Chol),
mPEG–Chol was used to prepare core-shell micelles encapsulating poorly water-soluble …

Doxorubicin Loading Capacity of Shell Cross-Linked Micelles with pH-Responsive Core as Anticancer Drug Delivery Nanocarriers

SY Zhu, ZL Niu, XT Zhang, DY Wang, JM Xu… - Materials Science …, 2017 - Trans Tech Publ
Detailed studies were performed to probe the effects of the cross-linking layer microstructure
of pH-responsive shell cross-linked (SCL) micelles on the loading capacity of doxorubicin …

Nanostructured lipid carriers modified with PEGylated carboxymethylcellulose polymers for effective delivery of docetaxel

W Jiang, J Wang, L Yang, X Jiang, Z Bai, Z Wang… - RSC …, 2015 - pubs.rsc.org
An amphiphilic carboxymethylcellulose-graft-histidine/methoxypolyethylene glycol (CMP)
copolymer was firstly synthesized to modify nanostructured lipid carriers (NLCs), and the …

Role of non-covalent and covalent interactions in cargo loading capacity and stability of polymeric micelles

X Ke, VWL Ng, RJ Ono, JMW Chan… - Journal of Controlled …, 2014 - Elsevier
Polymeric micelles self-assembled from biodegradable amphiphilic block copolymers have
been proven to be effective drug delivery carriers that reduce the toxicity and enhance the …

Polymer‐Stabilized Micelles Reduce the Drug Rapid Clearance In Vivo

SN Wen, CH Chu, YC Wang, HY Huang… - Journal of …, 2018 - Wiley Online Library
Micelles are self‐assembled nanoscaled aggregates from amphiphilic unimers and can be
used to encapsulate hydrophobic drugs. However, the dynamic exchanging of unimers …

[HTML][HTML] Self-assembly of cholesterol end-capped polymer micelles for controlled drug delivery

M Gao, Y Yang, A Bergfel, L Huang, L Zheng… - Journal of …, 2020 - Springer
Background During the past few decades, drug delivery system (DDS) has attracted many
interests because it could enhance the therapeutic effects of drugs and reduce their side …

[引用][C] Decreased Core Crystallinity Facilitated Drug Loading in Polymeric Micelles without Affecting Their Biological Performances

G Jingxin, F Shuangshuang, X Helin, F Guihua… - 2015

[HTML][HTML] A simple method to improve the stability of docetaxel micelles

L Zhang, LW Tan, LJ Chen, XX Chen, CF Long… - Scientific reports, 2016 - nature.com
Self-assembled polymeric micelles have been widely applied in drug delivery systems. In
this study, we found that pH value of micellar system solution was the decisive factor of …

Solubility enhancement and drug release mechanism of polymeric micelles

G Kenguva, SR Rout, M Fatima, SK Dubey… - Polymeric Micelles for …, 2022 - Elsevier
Polymeric micelles are one of the prominent nanocarriers used to deliver drugs. These
micelles are made up of amphiphilic copolymers that shape into a nanosized micellar …