Inhaled corticosteroid use is associated with increased circulating T regulatory cells in children with asthma

AM Singh, P Dahlberg, K Burmeister, MD Evans… - Clinical and Molecular …, 2013 - Springer
Background T regulatory (Treg) cells are important in balancing immune responses and
dysregulation of Treg cells has been implicated in the pathogenesis of multiple disease …

Natural regulatory T cells in isolated early responders compared with dual responders with allergic asthma

T Kinoshita, A Baatjes, SG Smith, B Dua… - Journal of Allergy and …, 2014 - Elsevier
Background Natural regulatory T (Treg) cells are implicated in the regulation of the
inflammatory response in patients with allergic asthma. Objectives We sought to determine …

Regulatory T cell levels in children with asthma

M Yüksek, F Erol, D Güloğlu, F Doğu… - The Turkish Journal …, 2011 - turkjpediatr.org
Natural regulatory T (nTreg) cells are described by expression of a specific transcription
factor, FOXP3, on CD4+ CD25+ cells. They play very important roles in the suppression of …

[HTML][HTML] Increased pro-inflammatory cytokine-secreting regulatory T cells are correlated with the plasticity of T helper cell differentiation and reflect disease status in …

L Xin, J Gao, X Ge, C Tian, W Ma, Z Tian, X Zheng… - Respiratory …, 2018 - Elsevier
Background Human regulatory T cells (Tregs) are a heterogeneous population which
consists of three distinct subpopulations: CD25+ CD45RA+ resting Treg (rTreg) cells; CD25 …

The levels of CD4+CD25+ regulatory T cells in paediatric patients with allergic rhinitis and bronchial asthma

JH Lee, HH Yu, LC Wang, YH Yang… - Clinical & …, 2007 - academic.oup.com
Our purpose was to determine whether numbers of CD4+ CD25+ T [T regulatory (Treg)] cells
and mRNA expression of functional molecules of Treg are related to airway allergy and …

Characterization of regulatory T cells in urban newborns

NP Ly, B Ruiz-Perez, RM McLoughlin… - Clinical and molecular …, 2009 - Springer
Abstract Background In the United States, asthma prevalence is particularly high among
urban children. Although the underlying immune mechanism contributing to asthma has not …

[HTML][HTML] Regulatory T cells in induced sputum of asthmatic children: association with inflammatory cytokines

A Hamzaoui, J Ammar… - Multidisciplinary …, 2010 - mrmjournal.biomedcentral.com
Background and objective: CD4+CD25+ regulatory T (Treg) cells play an essential role in
maintaining immune homeostasis. In this study, we investigated whether the induced …

Regulatory T cells in allergy and asthma

E Martín-Orozco, M Norte-Muñoz… - Frontiers in …, 2017 - frontiersin.org
The immune system's correct functioning requires a sophisticated balance between
responses to continuous microbial challenges and tolerance to harmless antigens, such as …

Increased airway T regulatory cells in asthmatic subjects

LJC Smyth, A Eustace, U Kolsum, J Blaikely, D Singh - Chest, 2010 - Elsevier
Background T regulatory cells (Tregs) may play a role in the suppression of effector
lymphocyte activity in asthma. We hypothesized that Treg numbers would be increased in …

The number and function of T regulatory cells in obese atopic female asthmatics

RI Cohen, X Ye, R Ramdeo, SF Liu - Journal of Asthma, 2019 - Taylor & Francis
Background: Mechanisms underlying the association between asthma and obesity remain
poorly understood. Obesity appears to be a risk factor for asthma, and obese asthmatics fare …