Polycystic ovary syndrome (PCOS) is the most common gynecological endocrine disorder.
The genetic background is believed to play a crucial role in the pathogenesis of PCOS. In …

Aim Recently, the roles of insulin receptor (INSR) and insulin receptor substrate (IRS)
polymorphisms in polycystic ovary syndrome (PCOS) have been extensively studied, with …

The insulin receptor (INSR), which is an indispensable component of the insulin-signalling
pathway, could be a plausible candidate gene for polycystic ovary syndrome (PCOS). This …

Polycystic ovary syndrome (PCOS) is a heterogeneous condition with unknown aetiology
which is considered to be the most common endocrine disorder in women of reproductive …

OBJECTIVE: To evaluate association with polycystic ovary syndrome (PCOS) of 295 variants
in 39 genes central to metabolic insulin signaling and glycogen synthase kinase 3β (GSK …

Background Insulin and its receptor (INSR) have been implicated in the etiology of the
polycystic ovarian syndrome (PCOS). Here, we investigate the association between INSR …

Background Polycystic ovary syndrome (PCOS) is a complex disease having both genetic
and environmental components. Candidate genes with insulin metabolism have been …

Objective This study is designed to determine whether an association exists between single
nucleotide polymorphism (SNP) variant rs2252673 of insulin receptor (INSR) gene and …

OBJECTIVE: To investigate several single nucleotide polymorphisms (SNPs) in the insulin
receptor (INSR) gene that have significant associations with pathogenesis of polycystic …

Sažetak Obesity and insulin resistance is a common finding in patients with polycystic ovary
syndrome (PCOS). Significant number of PCOS women experience insulin resistance that is …