Human papillomavirus genome integration and head and neck cancer

LM Pinatti, HM Walline… - Journal of dental …, 2018 - journals.sagepub.com
We conducted a critical review of human papillomavirus (HPV) integration into the host
genome in oral/oropharyngeal cancer, reviewed the literature for HPV-induced cancers, and …

[HTML][HTML] Causes and consequences of HPV integration in head and neck squamous cell carcinomas: state of the art

H Balaji, I Demers, N Wuerdemann, J Schrijnder… - Cancers, 2021 - mdpi.com
Simple Summary In human papillomavirus (HPV) associated head and neck squamous cell
carcinomas (HNSCC) s, the HPV genome is commonly found integrated in the human …

Human papillomavirus integration strictly correlates with global genome instability in head and neck cancer

B Labarge, M Hennessy, L Zhang, D Goldrich… - Molecular Cancer …, 2022 - AACR
Human papillomavirus (HPV)-positive head and neck cancers, predominantly
oropharyngeal squamous cell carcinoma (OPSCC), exhibit epidemiologic, clinical, and …

Integration of high‐risk human papillomavirus into cellular cancer‐related genes in head and neck cancer cell lines

HM Walline, CM Goudsmit, JB McHugh, AL Tang… - Head & …, 2017 - Wiley Online Library
Background Human papillomavirus (HPV)‐positive oropharyngeal cancer is generally
associated with excellent response to therapy, but some HPV‐positive tumors progress …

Diverse tumorigenic consequences of human papillomavirus integration in primary oropharyngeal cancers

DE Symer, K Akagi, HM Geiger, Y Song, G Li… - Genome …, 2022 - genome.cshlp.org
Human papillomavirus (HPV) causes 5% of all cancers and frequently integrates into host
chromosomes. The HPV oncoproteins E6 and E7 are necessary but insufficient for cancer …

Characterization of HPV and host genome interactions in primary head and neck cancers

M Parfenov, CS Pedamallu… - Proceedings of the …, 2014 - National Acad Sciences
Previous studies have established that a subset of head and neck tumors contains human
papillomavirus (HPV) sequences and that HPV-driven head and neck cancers display …

The role of viral integration in the development of cervical cancer

T Yu, MJ Ferber, TH Cheung, TKH Chung… - Cancer genetics and …, 2005 - Elsevier
The development of invasive cervical cancer is associated with human papillomavirus (HPV)
infection and subsequent integration into the host epithelium. More than 99% of cervical …

Human papilloma virus integration sites and genomic signatures in head and neck squamous cell carcinoma

J Mainguené, S Vacher, M Kamal, A Hamza… - Molecular …, 2022 - Wiley Online Library
A prevalence of around 26% of human papillomavirus (HPV) in head and neck squamous
cell carcinoma (HNSCC) has been previously reported. HPV induced oncogenesis mainly …

HPV integration in head and neck squamous cell carcinomas: cause and consequence

EJM Speel - HPV infection in head and neck cancer, 2017 - Springer
Human papillomaviruses (HPVs) are a necessary cause of anogenital squamous cell
carcinomas (SCC) and a subgroup of head and neck SCC, ie, those originating in the …

Identification of human papillomavirus (HPV) 16 DNA integration and the ensuing patterns of methylation in HPV‐associated head and neck squamous cell carcinoma …

T Hatano, D Sano, H Takahashi… - … journal of cancer, 2017 - Wiley Online Library
Recent studies showed that human papillomavirus (HPV) integration contributes to the
genomic instability seen in HPV‐associated head and neck squamous cell carcinoma (HPV …