Integration of the full-length HPV16 genome in cervical cancer and Caski and Siha cell lines and the possible ways of HPV integration

F Xu, M Cao, Q Shi, H Chen, Y Wang, X Li - Virus Genes, 2015 - Springer
Integration of high-risk human papillomavirus (HPV) into the host genome is a key event for
cervical carcinogenesis. Different methods have been used to explore the physical states of …

HPV integration detection in CaSki and SiHa using detection of integrated papillomavirus sequences and restriction-site PCR

R Raybould, A Fiander, GWG Wilkinson… - Journal of virological …, 2014 - Elsevier
Human Papillomavirus (HPV) infection is the primary cause of cervical neoplasia. HPV DNA
is integrated into the human genome in the majority of cervical cancers. The nature of …

HPV integration hijacks and multimerizes a cellular enhancer to generate a viral-cellular super-enhancer that drives high viral oncogene expression

A Warburton, CJ Redmond, KE Dooley, H Fu… - PLoS …, 2018 - journals.plos.org
Integration of human papillomavirus (HPV) genomes into cellular chromatin is common in
HPV-associated cancers. Integration is random, and each site is unique depending on how …

Do human papillomavirus infections cause oral cancer?

KV Shah - Journal of the National Cancer Institute, 1998 - academic.oup.com
The etiologic link between infections of the genital tract with human papillomavirus (HPV)
and invasive cervical cancer was established when the mutually corroborative evidence …

Preferential integration of human papillomavirus type 18 near the c-myc locus in cervical carcinoma

MJ Ferber, EC Thorland, AATP Brink, AK Rapp… - Oncogene, 2003 - nature.com
The development of cervical cancer is highly associated with human papillomavirus (HPV)
infection. Greater than 99% of all cervical tumors contain HPV DNA. Integration of high-risk …

Mechanistic signatures of human papillomavirus insertions in anal squamous cell carcinomas

A Morel, C Neuzillet, M Wack, S Lameiras, S Vacher… - Cancers, 2019 - mdpi.com
The role of human papillomavirus (HPV) in anal squamous cell carcinoma (ASCC)
carcinogenesis has been clearly established, involving the expression of viral oncoproteins …

Tissue distribution of human papillomavirus 16 DNA integration in patients with tonsillar carcinoma

S Begum, D Cao, M Gillison, M Zahurak… - Clinical Cancer Research, 2005 - AACR
Abstract Purpose: Human papillomavirus 16 (HPV-16) has been implicated as a causative
agent in a subset of head and neck squamous cell carcinomas (HNSCC). This study was …

Detection of integrated papillomavirus sequences by ligation‐mediated PCR (DIPS‐PCR) and molecular characterization in cervical cancer cells

F Luft, R Klaes, M Nees, M Dürst… - … journal of cancer, 2001 - Wiley Online Library
Human papillomavirus (HPV) genomes usually persist as episomal molecules in HPV
associated preneoplastic lesions whereas they are frequently integrated into the host cell …

Genomic landscape of human papillomavirus–associated cancers

M Rusan, YY Li, PS Hammerman - Clinical cancer research, 2015 - AACR
Recent next-generation sequencing studies have generated a comprehensive overview of
the genomic landscape of human papillomavirus (HPV)–associated cancers. This review …

[HTML][HTML] Patients with integrated HPV16 in head and neck cancer show poor survival

TJ Nulton, NK Kim, LJ DiNardo, IM Morgan, B Windle - Oral oncology, 2018 - Elsevier
Objectives We previously reported identifying three categories of HPV16-positive head and
neck tumors based on The Cancer Genome Atlas (TCGA) RNA and DNA sequence data …