[HTML][HTML] Transcriptomic predictors of paradoxical cryptococcosis-associated immune reconstitution inflammatory syndrome

IVS Louis, CC Chang, S Shahid… - Open Forum …, 2018 - ncbi.nlm.nih.gov
Background Paradoxical cryptococcosis-associated immune reconstitution inflammatory
syndrome (C-IRIS) affects~ 25% of human immunodeficiency virus (HIV)-infected patients …

Transcriptomic predictors of paradoxical cryptococcosis-associated immune reconstitution inflammatory syndrome

I Vlasova-St. Louis, CC Chang, S Shahid… - Open forum …, 2018 - academic.oup.com
Background Paradoxical cryptococcosis-associated immune reconstitution inflammatory
syndrome (C-IRIS) affects~ 25% of human immunodeficiency virus (HIV)-infected patients …

Plasma but not cerebrospinal fluid interleukin 7 and interleukin 5 levels pre–antiretroviral therapy commencement predict cryptococcosis-associated immune …

NA Akilimali, CC Chang, DM Muema… - Clinical Infectious …, 2017 - academic.oup.com
Background Patients with human immunodeficiency virus/AIDS-associated cryptococcal
meningitis (CM) frequently experience clinical deterioration, known as cryptococcosis …

[HTML][HTML] Transcriptomic biomarker pathways associated with death in HIV-infected patients with cryptococcal meningitis

I Vlasova-St Louis, AK Musubire, DB Meya… - BMC Medical …, 2021 - Springer
Background Cryptococcal meningitis (CM) is a major cause of death in HIV-infected patients
in sub-Saharan Africa. Many CM patients experience cryptococcosis-associated immune …

Cryptococcosis-IRIS is Associated With Lower Cryptococcus-specific IFN-γ Responses Before Antiretroviral Therapy but Not Higher T-Cell Responses During …

CC Chang, A Lim, S Omarjee, SM Levitz… - The Journal of …, 2013 - academic.oup.com
Background. Cryptococcosis-associated immune reconstitution inflammatory syndrome (C-
IRIS) may be driven by aberrant T-cell responses against cryptococci. We investigated this in …

[HTML][HTML] A nomogram for predicting paradoxical immune reconstitution inflammatory syndrome associated with cryptococcal meningitis among HIV-infected individuals …

X Han, H Liu, Y Wang, P Wang, X Wang, Y Yi… - AIDS research and …, 2022 - Springer
Background Cryptococcal meningitis (CM) associated immune reconstitution inflammatory
syndrome (CM-IRIS) is the second most common complication in HIV-infected individuals …

[HTML][HTML] Cryptococcal immune reconstitution inflammatory syndrome: from blood and cerebrospinal fluid biomarkers to treatment approaches

VMS Brienze, JC André, E Liso, I Vlasova-St. Louis - Life, 2021 - mdpi.com
Immune reconstitution inflammatory syndrome (IRIS) presents as an exaggerated immune
reaction that occurs during dysregulated immune restoration in immunocompromised …

Understanding causal pathways in cryptococcal meningitis immune reconstitution inflammatory syndrome

JN Jarvis, TS Harrison - The Journal of infectious diseases, 2019 - academic.oup.com
Human immunodeficiency virus (HIV)-associated cryptococcal meningitis continues to pose
a major clinical challenge. Mortality rates of 20%–40% have been reported in recent clinical …

[HTML][HTML] Paradoxical immune reconstitution inflammatory syndrome associated with cryptococcal meningitis in China: a 5-year retrospective cohort study

S Yan, L Chen, W Wu, Z Li, Z Fu, H Zhang, J Xue… - Clinical Microbiology …, 2015 - Elsevier
We performed a retrospective cohort study of hospitalised cryptococcal meningitis (CM)
patients at a single centre to evaluate the clinical epidemiological features of paradoxical …

[HTML][HTML] Clinical features and serum biomarkers in HIV immune reconstitution inflammatory syndrome after cryptococcal meningitis: a prospective cohort study

DR Boulware, DB Meya, TL Bergemann… - PLoS …, 2010 - journals.plos.org
Background Although antiretroviral therapy (ART) improves survival in persons with
cryptococcal meningitis (CM) and AIDS, ART frequently elicits HIV immune reconstitution …