Prostatic intraepithelial neoplasia

DG Bostwick - Current urology reports, 2000 - Springer
High-grade prostatic intraepithelial neoplasia (PIN) is now accepted as the most likely pre-
invasive stage of adenocarcinoma, a decade after its first formal description. PIN has a high …

High‐grade prostatic intraepithelial neoplasia is an independent predictor of outcome after radical prostatectomy

PM Pierorazio, SM Lambert, M Matsukhani… - BJU …, 2007 - Wiley Online Library
OBJECTIVE To examine the relationship between the presence of high‐grade prostatic
intraepithelial neoplasia (HGPIN) in retropubic radical prostatectomy (RP) specimens and …

Evolution of isolated high-grade prostate intraepithelial neoplasia in a Mediterranean patient population

F Algaba - European urology, 1999 - karger.com
The discovery of high-grade prostatic intraepithelial neoplasia (HGPIN) in prostatic needle
biopsies is of clinical importance. Previous studies have shown prostate cancer to develop …

Precancerous lesions and conditions of the prostate: from morphological and biological characterization to chemoprevention

R Montironi, R Mazzucchelli… - Annals of the New York …, 2002 - Wiley Online Library
Prostatic intraepithelial neoplasia (PIN) is composed of dysplastic cells with a luminal cell
phenotype, expressing the androgen receptor as well as prostate‐specific antigen. PIN is …

Prostatic intraepithelial neoplasia is a risk factor for cancer.

DG Bostwick - Seminars in urologic oncology, 1999 - europepmc.org
High-grade prostatic intraepithelial neoplasia (PIN) is now accepted as the most likely
preinvasive stage of adenocarcinoma, a decade after its first formal description. PIN has a …

Intermediate biomarkers for chemoprevention of prostate cancer.

TH Van Der Kwast - IARC Scientific Publications, 2001 - europepmc.org
Use of high-grade prostatic intraepithelial neoplasia (PIN) as an intermediate biomarker for
prostate cancer requires additional data concerning its natural biological behaviour …

Prospective study of correlations between biopsy‐detected high grade prostatic intraepithelial neoplasia, serum prostate specific antigen concentration, and race

JE Fowler Jr, SA Bigler, C Lynch, SS Wilson… - Cancer, 2001 - Wiley Online Library
BACKGROUND High grade prostatic intraepithelial neoplasia (HGPIN), a premalignant
lesion of the prostate gland, is more common in black men than in white men. The influence …

Cell-based evidence regarding the role of FSH in prostate cancer

N Dizeyi, D Trzybulska, Y Al-Jebari, I Huhtaniemi… - … Oncology: Seminars and …, 2019 - Elsevier
Introduction Conversion of androgen-responsive prostate cancer (CaP) to castration-
resistant CaP is associated with an acceleration of the disease that often requires treatment …

Flutamide as an alternative anti-androgen agent and predictor of the efficacy of novel androgen receptor-targeted agents

N Yamaguchi, S Morizane, T Yumioka… - Anticancer …, 2019 - ar.iiarjournals.org
Background/Aim: There are few reports that verify the relationship between the therapeutic
effects of flutamide and novel androgen receptor-targeted agents. We aimed to evaluate the …

Expression of ERG protein, a prostate cancer specific marker, in high grade prostatic intraepithelial neoplasia (HGPIN): lack of utility to stratify cancer risks associated …

H He, AO Osunkoya, P Carver, S Falzarano… - BJU …, 2012 - Wiley Online Library
Study Type–Diagnosis (cohort) Level of Evidence 2b What's known on the subject? and
What does the study add? High grade prostatic intraepithelial neoplasia is a pre‐malignant …