Pathological changes of high‐grade prostatic intraepithelial neoplasia and prostate cancer after monotherapy with bicalutamide 150 mg

V Scattoni, R Montironi, R Mazzucchelli… - BJU …, 2006 - Wiley Online Library
OBJECTIVES To evaluate the morphological changes induced by a 3‐month course of
neoadjuvant bicalutamide 150 mg/day before radical prostatectomy (RP) on prostatic …

Prognostic significance of high-grade prostatic intraepithelial neoplasia (HGPIN): risk of prostatic cancer on repeat biopsies

F Gallo, L Chiono, E Gastaldi, E Venturino, C Giberti - Urology, 2008 - Elsevier
OBJECTIVES: To verify prognostic significance of high-grade prostatic intraepithelial
neoplasia (HGPIN) in 65 patients who underwent repeat biopsies with a mean follow-up of …

Tolerability and safety of flutamide in monotherapy, with orchiectomy or with LHRH-a in advanced prostate cancer patients

W Oosterlinck, J Casselman, J Mattelaer… - European …, 1996 - karger.com
Objective: In a multicenter study, 905 patients with newly diagnosed advanced prostate
cancer treated with flutamide were followed for safety and side effects. Methods: Flutamide …

High-Grade Prostatic Intraepithelial Neoplasia in Patients with Prostate Cancer: MR and MR Spectroscopic Imaging Features—Initial Experience1

JJ Hom, FV Coakley, JP Simko, Y Lu, A Qayyum… - Radiology, 2007 - pubs.rsna.org
Purpose: To retrospectively determine the magnetic resonance (MR) and MR spectroscopic
imaging features of high-grade prostatic intraepithelial neoplasia (HGPIN) in patients with …

Gene expression profile of primary prostate epithelial and stromal cells in response to sulforaphane or iberin exposure

KF Chambers, JR Bacon, EK Kemsley, RD Mills… - The …, 2009 - Wiley Online Library
BACKGROUND Broccoli consumption has been associated with a reduced risk of prostate
cancer. Isothiocyanates (ITCs) derived from glucosinolates that accumulate in broccoli are …

Prostatic intraepithelial neoplasia and prostate cancer.

R Montironi, A Santinelli, R Mazzucchelli - Panminerva medica, 2002 - europepmc.org
Prostatic intraepithelial neoplasia (PIN) is composed of dysplastic cells with a luminal cell
phenotype, expressing the androgen receptor as well as prostate specific antigen. PIN is …

Prostate-specific antigen modulates the expression of genes involved in prostate tumor growth

B Bindukumar, SA Schwartz, MPN Nair, R Aalinkeel… - Neoplasia, 2005 - Elsevier
Prostate-specific antigen (PSA) is a serine protease that is widely used as a surrogate
marker in the early diagnosis and management of prostate cancer. The physiological …

The prevalence of high‐grade prostatic intraepithelial neoplasia in surgical resection specimens: An Indian experience

SB Desai, AM Borges - … Journal of the American Cancer Society, 2002 - Wiley Online Library
BACKGROUND To the authors' knowledge there is a paucity of literature regarding the
prevalence of high‐grade prostatic intraepithelial neoplasia (HGPIN) in the Indian …

Finasteride and flutamide therapy in patients with advanced prostate cancer: response to subsequent castration and long-term follow-up

WK Oh, J Manola, L Bittmann, A Brufsky, ID Kaplan… - Urology, 2003 - Elsevier
OBJECTIVES: To report the efficacy of castration after progression on finasteride and
flutamide. Standard androgen deprivation strategies for prostate cancer typically lead to …

PSA decrease with fulvestrant acetate in a hormone-resistant metastatic prostate cancer patient

JM Gasent Blesa, V Alberola Candel - Oncology Research and …, 2010 - karger.com
Background: Androgen-independent prostate cancer (AIPCA) is a difficult disease to treat.
Fulvestrant has shown activity inhibiting estrogen receptor dimerization, and the androgen …