[HTML][HTML] Circulating tumor cells: finding the needle in the haystack

X Zhe, ML Cher, RD Bonfil - American journal of cancer research, 2011 - ncbi.nlm.nih.gov
Localized and metastatic cancers give rise to circulating tumor cells (CTCs) which are
detectable in the bloodstream. Recent studies have highlighted the prognostic significance …

Circulating tumor cells: evolving evidence and future challenges

E Dotan, SJ Cohen, KR Alpaugh, NJ Meropol - The oncologist, 2009 - academic.oup.com
Circulating tumor cells (CTCs) are rare malignant cells found in the peripheral blood that
originate from the primary tumor or metastatic sites. New techniques have been developed …

Circulating tumor cells: advances in detection methods, biological issues, and clinical relevance

YF Sun, XR Yang, J Zhou, SJ Qiu, J Fan… - Journal of cancer research …, 2011 - Springer
Abstract Background Circulating tumor cells (CTCs) have long been considered a reflection
of tumor aggressiveness. Hematogenous spreading of CTCs from a primary tumor is a …

Circulating tumor cells: from bench to bedside

M Balic, A Williams, H Lin, R Datar… - Annual review of …, 2013 - annualreviews.org
Circulating tumor cells (CTCs) represent a surrogate biomarker of hematogenous
metastases. In recent years, their detection has gained increasing interest. There is ample …

Circulating tumor cells as promising novel biomarkers in solid cancers

ES Lianidou, A Strati, A Markou - Critical reviews in clinical …, 2014 - Taylor & Francis
The presence of circulating tumor cells (CTCs) in peripheral blood can serve as a “liquid
biopsy” approach and has thus emerged lately as one of the hottest fields in cancer …

Circulating tumor cells (CTC's): Early assessment of time to progression, survival and response to therapy in metastatic cancer patients

J Allard, M Cristofanilli, L Terstappen - US Patent App. 11/202,875, 2007 - Google Patents
A cancer test having prognostic utility in predicting time to disease progression, overall
survival, and response to therapy in patients with MBC based upon the presence and …

[HTML][HTML] Circulating cancer cells

D Mavroudis - Annals of oncology, 2010 - Elsevier
Circulating tumour cells (CTCs) can be detected in the blood of many patients with different
types of early or advanced cancer using antibody-based assays or molecular methods. In …

Isolation of rare circulating tumor cells in cancer patients: technical aspects and clinical implications

M Danova, M Torchio, G Mazzini - Expert review of molecular …, 2011 - Taylor & Francis
Circulating tumor cells (CTCs) may be detected in the blood of patients with epithelial tumors
using different analytical approaches. The relative number of CTCs is low and they include a …

[HTML][HTML] Circulating cancer stem cells: the importance to select

MH Yang, A Imrali, C Heeschen - Chinese Journal of Cancer …, 2015 - ncbi.nlm.nih.gov
It has been demonstrated that even localized tumors without clinically apparent metastasis
give rise to circulating tumor cells (CTCs). A growing number of technically diverse platforms …

Circulating tumor cells: a review of present methods and the need to identify heterogeneous phenotypes

LM Millner, MW Linder… - Annals of Clinical & …, 2013 - Assoc Clin Scientists
The measurement and characterization of circulating tumor cells (CTCs) hold promise for
advancing personalized therapeutics. CTCs are the precursor to metastatic cancer and thus …