CYP3A4 and MDR1 alleles in a Portuguese population
Polymorphisms in cytochrome P450 CYP3A4 and multidrug resistance (MDR) 1 genes
coding for the important drugmetabolising CYP3A4 and the ATP-binding cassette (ABC) …
coding for the important drugmetabolising CYP3A4 and the ATP-binding cassette (ABC) …
[引用][C] CYP3A4, CYP3A5 and MDR‐1 variant alleles in the Dutch Caucasian population
R Van Schaik, M Van der Werf… - Clinical …, 2003 - Wiley Online Library
CYP3A4, CYP3A5 and MDRâ•’1 Variant Alleles in The Dutch Caucasian Population Page 1
CLINICAL PHARMACOLOGY & TH ERAPEUTICS P42 American Society Cbr Clinical …
CLINICAL PHARMACOLOGY & TH ERAPEUTICS P42 American Society Cbr Clinical …
Differences in CYP3A5* 3 genotype distribution and combinations with other polymorphisms between Spaniards and other Caucasian populations
G Gervasini, S Vizcaino, C Gasiba… - Therapeutic drug …, 2005 - journals.lww.com
The goal of this study was to detect genotypic differences between Spaniards and other
related populations regarding CYP3A4* 1B, CYP3A5* 3, and ABCB1 (MDR1) C3435T …
related populations regarding CYP3A4* 1B, CYP3A5* 3, and ABCB1 (MDR1) C3435T …
CYP3A5* 3 and MDR-1 C3435T single nucleotide polymorphisms in six Chinese ethnic groups
The prevalent CYP3A5* 3 and the functional multi-drug resistance gene (MDR1) C3435T
show marked interethnic variation among Orientals, Caucasians and Africans. This study …
show marked interethnic variation among Orientals, Caucasians and Africans. This study …
Genetic polymorphisms in MDR1 and CYP3A5 and MDR1 haplotype in mainland Chinese Han, Uygur and Kazakh ethnic groups
D Li, GL Zhang, YQ Lou, Q Li, X Wang… - Journal of clinical …, 2007 - Wiley Online Library
Background and objective: The drug transporter MDR1 and the drug metabolizing enzyme
CYP3A are the two major biological factors determining the pharmacokinetics of many …
CYP3A are the two major biological factors determining the pharmacokinetics of many …
Design of allele specific PCR for rapid detection of CYP3A5 (A6986G) and Mdr-1 (C3435T) polymorphisms
Single nucleotide polymorphisms in CYP3A5 (A6986G) and MDR-1 (C3435T) genes have
been shown to be associated with the pharmacokinetics of tacrolimus in case of renal …
been shown to be associated with the pharmacokinetics of tacrolimus in case of renal …
Characterization of pharmacogenetically relevant CYP2D6 and ABCB1 gene polymorphisms in a Portuguese population sample
C Correia, P Santos, AM Coutinho… - Cell Biochemistry and …, 2009 - Wiley Online Library
Differences in metabolism of drugs can lead to severe toxicity or therapeutic failure. In
addition to cytochrome P450 2D6, which plays a critical role in drug metabolism, ABCB1 …
addition to cytochrome P450 2D6, which plays a critical role in drug metabolism, ABCB1 …
CYP3A activity measured by the midazolam test is not related to 3435 C> T polymorphism in the multiple drug resistance transporter gene
A recent study with 69 Japanese liver transplants treated with tacrolimus found that the
MDR1 3435 C> T polymorphism, but not the MDR1 2677 G> T polymorphism, was …
MDR1 3435 C> T polymorphism, but not the MDR1 2677 G> T polymorphism, was …
Genetic polymorphism of cytochrome P450s and P‐glycoprotein in the Finnish population
J Hilli, A Rane, S Lundgren… - Fundamental & …, 2007 - Wiley Online Library
The objective of this study was to investigate the genetic polymorphism of selected
cytochrome P450 (CYP) enzymes and ABCB1 (encoding P‐glycoprotein) of central …
cytochrome P450 (CYP) enzymes and ABCB1 (encoding P‐glycoprotein) of central …
MDR1 genotype is associated with hepatic cytochrome P450 3A4 basal and induction phenotype
Objectives Variant cytochrome P450 (CYP) 3A4 alleles cannot explain human variation in
CYP3A4 expression. This study investigated whether common single‐nucleotide …
CYP3A4 expression. This study investigated whether common single‐nucleotide …