A new role for the Krüppel-like transcription factor KLF6 as an inhibitor of c-Jun proto-oncoprotein function

DA Slavin, NP Koritschoner, CC Prieto, FJ López-Díaz… - Oncogene, 2004 - nature.com
Krüppel-like transcription factors (KLFs) represent one of the most diverse set of regulators
in vertebrate organisms. KLF family members are involved in cell proliferation and …

Krüppel-like factor 4 regulates pressure-induced cardiac hypertrophy

X Liao, SM Haldar, Y Lu, D Jeyaraj, K Paruchuri… - Journal of molecular and …, 2010 - Elsevier
Krüppel-like factors (KLF) are a subfamily of the zinc-finger class of transcriptional regulators
that play important roles in diverse cellular processes. While a number of KLFs are …

The roles and regulation of the KLF5 transcription factor in cancers

Y Luo, C Chen - Cancer science, 2021 - Wiley Online Library
Krüppel‐like factor 5 (KLF5) is a member of the KLF family. Recent studies have suggested
that KLF5 regulates the expression of a large number of new target genes and participates …

[HTML][HTML] The emerging role of Krüppel-like factors in endocrine-responsive cancers of female reproductive tissues

RCM Simmen, JMP Pabona, MC Velarde… - The Journal of …, 2010 - ncbi.nlm.nih.gov
Krüppel-like factors (KLFs), of which there are currently 17 known protein members, belong
to the Specificity-protein (Sp) family of transcription factors and are characterized by the …

Developmental expression of the mouse gene coding for the Krüppel‐like transcription factor KLF5

S Ohnishi, F Laub, N Matsumoto… - … dynamics: an official …, 2000 - Wiley Online Library
The mammalian Kruppel-like transcription factors are key regulators of multiple
morphogenetic programs. Here, we examined the developmental expression of the mouse …

Krüppel-like factor 5 shows proliferation-specific roles in vascular remodeling, direct stimulation of cell growth, and inhibition of apoptosis

T Suzuki, D Sawaki, K Aizawa, Y Munemasa… - Journal of Biological …, 2009 - ASBMB
Krüppel-like factor 5 (KLF5), originally isolated as a regulator of phenotypic modulation of
vascular smooth muscle cells, induces pathological cell growth and is expressed in the …

KLF2 inhibits Jurkat T leukemia cell growth via upregulation of cyclin-dependent kinase inhibitor p21WAF1/CIP1

J Wu, JB Lingrel - Oncogene, 2004 - nature.com
Krüppel-like factor 2 (KLF2) is a member of the KLF family of zinc-finger transcription factors
and is involved in maintaining T-cell quiescence, regulating preadipocyte differentiation …

Regulation of KLF4 turnover reveals an unexpected tissue-specific role of pVHL in tumorigenesis

AM Gamper, X Qiao, J Kim, L Zhang, MC DeSimone… - Molecular cell, 2012 - cell.com
The transcription factor Krüppel-like factor 4 (KLF4) is an important regulator of cell-fate
decision, including cell-cycle regulation, apoptosis, and stem cell renewal, and plays an …

[HTML][HTML] Differential regulation of Krüppel-like factor family transcription factor expression in neonatal rat cardiac myocytes: effects of endothelin-1, oxidative stress and …

TE Cullingford, MJ Butler, AK Marshall… - … et Biophysica Acta (BBA …, 2008 - Elsevier
Krüppel-like transcription factors (Klfs) modulate fundamental cell processes. Cardiac
myocytes are terminally-differentiated, but hypertrophy in response to stimuli such as …

SP and KLF transcription factors in digestive physiology and diseases

CK Kim, P He, AB Bialkowska, VW Yang - Gastroenterology, 2017 - Elsevier
Specificity proteins (SPs) and Krüppel-like factors (KLFs) belong to the family of transcription
factors that contain conserved zinc finger domains involved in binding to target DNA …