Abstract Hydrogen peroxide (H 2 O 2) is an incompletely reduced metabolite of oxygen that
has a diverse array of physiological and pathological effects within living cells depending on …

Intracellular generation of reactive oxygen species (ROS) is an inescapable consequence of
aerobic metabolism. Although some of these oxygen-derived metabolites are well …

Hydrogen peroxide (H2O2) is a potent small-molecule oxidant that can exert a diverse array
of physiological and/or pathological effects within living systems depending on the timing …

Background Life is a constant flow of electrons via redox couples. Redox reactions
determine many if not all major cellular functions. Until recently, redox processes remained …

Abstract Significance: Hydrogen peroxide (H2O2) is a powerful effector of redox signaling. It
is able to oxidize cysteine residues, metal ion centers, and lipids. Understanding H2O2 …

Reactive oxygen species (ROS) are conserved regulators of numerous cellular functions,
and overproduction of ROS is a hallmark of various pathological processes. Genetically …

Addition of hydrogen peroxide (H2O2) is a method commonly used to trigger cellular
oxidative stress. However, the doses used (often hundreds of micromolar) are …

Mounting evidence supports the role of hydrogen peroxide (H 2 O 2) in physiological
signaling as well as pathological conditions. However, the subtleties of peroxide-mediated …

In this study, we propose a method for quantification of average hydrogen peroxide
concentration within a living cell that is based on the use of genetically encoded H 2 O 2 …

The concentration of hydrogen peroxide (H 2 O 2) in blood and plasma is a measurement
that has often been made, but the absolute values remain unsettled due the great variability …