Smoking and lung cancer: a geo-regional perspective

Z Rahal, S El Nemr, A Sinjab, H Chami, A Tfayli… - Frontiers in …, 2017 - frontiersin.org
Lung cancer is the leading cause of cancer-related deaths worldwide. Non-small cell lung
cancer (NSCLC) represents the most frequently diagnosed subtype of this morbid …

New molecular insights in tobacco-induced lung cancer

G Tonini, L D'Onofrio, E Dell'Aquila, A Pezzuto - Future Oncology, 2013 - Taylor & Francis
We know that cigarette smoking is a leading preventable cause of carcinogenesis in lung
cancer. Cigarette smoke is a mixture of more than 5000 chemical compounds, among which …

Genomic and transcriptional alterations in lung adenocarcinoma in relation to smoking history

A Karlsson, M Ringnér, M Lauss, J Botling, P Micke… - Clinical Cancer …, 2014 - AACR
Purpose: Cigarette smoking is the major pathogenic factor for lung cancer. The precise
mechanisms of tobacco-related carcinogenesis and its effect on the genomic and …

[HTML][HTML] Global epidemiology of lung cancer

JA Barta, CA Powell, JP Wisnivesky - Annals of global health, 2019 - ncbi.nlm.nih.gov
While lung cancer has been the leading cause of cancer-related deaths for many years in
the United States, incidence and mortality statistics–among other measures–vary widely …

[HTML][HTML] Global trends of lung cancer mortality and smoking prevalence

F Islami, LA Torre, A Jemal - Translational lung cancer research, 2015 - ncbi.nlm.nih.gov
Abstract Lung cancer killed approximately 1,590,000 persons in 2012 and currently is the
leading cause of cancer death worldwide. There is large variation in mortality rates across …

Molecular changes in smoking-related lung cancer

S Begum - Expert Review of Molecular Diagnostics, 2012 - Taylor & Francis
To elucidate the effect of cigarette smoke on developing lung cancer among individuals,
numerous genetic and epigenetic factors related to cigarette smoke-induced lung cancers …

Lung cancer mortality in the wake of the changing smoking epidemic: a descriptive study of the global burden in 2020 and 2040

A Wéber, E Morgan, J Vignat, M Laversanne… - BMJ open, 2023 - bmjopen.bmj.com
Objectives Lung cancer (LC) is the leading cause of cancer death in 2020, responsible for
almost one in five (18.0%) deaths. This paper provides an overview of the descriptive …

[HTML][HTML] The International Epidemiology of Lung Cancer: geographical distribution and secular trends

DR Youlden, SM Cramb, PD Baade - Journal of thoracic oncology, 2008 - Elsevier
This review presents the latest available international data for lung cancer incidence,
mortality and survival, emphasizing the established causal relationship between smoking …

Non-smoking-associated lung cancer: a distinct entity in terms of tumor biology, patient characteristics and impact of hereditary cancer predisposition

E Smolle, M Pichler - Cancers, 2019 - mdpi.com
Non-small cell lung cancer (NSCLC) in non-, and especially in never-smoking patients is
considered a biologically unique type of lung cancer, since risk factors and tumorigenic …

Gene expression signature of cigarette smoking and its role in lung adenocarcinoma development and survival

MT Landi, T Dracheva, M Rotunno, JD Figueroa, H Liu… - PloS one, 2008 - journals.plos.org
Background Tobacco smoking is responsible for over 90% of lung cancer cases, and yet the
precise molecular alterations induced by smoking in lung that develop into cancer and …