Control of adipocyte differentiation in different fat depots; implications for pathophysiology or therapy

X Ma, P Lee, DJ Chisholm, DE James - Frontiers in endocrinology, 2015 - frontiersin.org
Adipocyte differentiation and its impact on restriction or expansion of particular adipose
tissue depots have physiological and pathophysiological significance in view of the different …

Mechanisms linking adipose tissue inflammation to cardiac hypertrophy and fibrosis

SR Anthony, AR Guarnieri, A Gozdiff… - Clinical …, 2019 - portlandpress.com
Adipose tissue is classically recognized as the primary site of lipid storage, but in recent
years has garnered appreciation for its broad role as an endocrine organ comprising …

Obesity, adipose tissue and vascular dysfunction

M Koenen, MA Hill, P Cohen, JR Sowers - Circulation research, 2021 - Am Heart Assoc
Cardiovascular diseases are the leading cause of death worldwide. Overweight and obesity
are strongly associated with comorbidities such as hypertension and insulin resistance …

Adipose tissue, inflammation, and cardiovascular disease

AH Berg, PE Scherer - Circulation research, 2005 - Am Heart Assoc
Mounting evidence highlights the role of adipose tissue in the development of a systemic
inflammatory state that contributes to obesity-associated vasculopathy and cardiovascular …

Revisiting the adipocyte: a model for integration of cytokine signaling in the regulation of energy metabolism

A Rodríguez, S Ezquerro… - American Journal …, 2015 - journals.physiology.org
Adipose tissue constitutes an extremely active endocrine organ with a network of signaling
pathways enabling the organism to adapt to a wide range of different metabolic challenges …

Recruitment of brown adipose tissue as a therapy for obesity-associated diseases

O Boss, SR Farmer - Frontiers in endocrinology, 2012 - frontiersin.org
Brown adipose tissue (BAT) has been recognized for more than 20 years to play a key role
in cold-induced non-shivering thermogenesis (CIT, NST), and body weight homeostasis in …

Adipose tissue in health and disease

I Harvey, A Boudreau, JM Stephens - Open biology, 2020 - royalsocietypublishing.org
Adipose, or fat, tissue (AT) was once considered an inert tissue that primarily existed to store
lipids, and was not historically recognized as an important organ in the regulation and …

[HTML][HTML] Chronic adipose tissue inflammation linking obesity to insulin resistance and type 2 diabetes

F Zatterale, M Longo, J Naderi, GA Raciti… - Frontiers in …, 2020 - frontiersin.org
Obesity is one of the major health burdens of the 21st century as it contributes to the growing
prevalence of its related comorbidities, including insulin resistance and type 2 diabetes …

Regulation of visceral and epicardial adipose tissue for preventing cardiovascular injuries associated to obesity and diabetes

N González, Z Moreno-Villegas… - Cardiovascular …, 2017 - Springer
Nowadays, obesity is seriously increasing in most of the populations all over the world, and
is associated with the development and progression of high-mortality diseases such as type …

Adipose tissue remodeling: its role in energy metabolism and metabolic disorders

SS Choe, JY Huh, IJ Hwang, JI Kim… - Frontiers in …, 2016 - frontiersin.org
The adipose tissue is a central metabolic organ in the regulation of whole-body energy
homeostasis. The white adipose tissue functions as a key energy reservoir for other organs …