Obesity is a critical risk factor for the development of type 2 diabetes (T2D), and its
prevalence is rising worldwide. White adipose tissue (WAT) has a crucial role in regulating …

The prevalence of obesity and associated chronic diseases continues to increase
worldwide, negatively impacting on societies and economies. Whereas the association …

White adipose tissue (WAT) has key metabolic and endocrine functions and plays a role in
regulating energy homeostasis and insulin sensitivity. WAT is characterised by its capacity to …

Major shifts in human lifestyle and dietary habits toward sedentary behavior and refined food
intake triggered steep increase in the incidence of metabolic disorders including obesity and …

Inflammation originating from the adipose tissue is considered to be one of the main driving
forces for the development of insulin resistance and type 2 diabetes in obese individuals …

Obesity is a significant health challenge, with the latest projections estimating that there will
be 2.16 billion overweight and 1.12 billion obese individuals globally by 2030. In addition to …

Like the obesity epidemic, our understanding of adipocytes and adipose tissue is
expanding. Just in the past decade, substantial advances have led to new insights into the …

Obesity is frequently associated with chronic inflammation, metabolic and vascular
alterations which predispose to the development of the Metabolic Syndrome (MetS) …

This review focuses on the contribution of white, brown, and perivascular adipose tissues to
the pathophysiology of obesity and its associated metabolic and vascular complications …

Obesity-associated insulin resistance is a complex disorder involving a number of candidate
molecules, pathways and transduction systems possessing potential causal actions …