Metabolic syndrome, insulin resistance, and roles of inflammation–mechanisms and therapeutic targets
GR Romeo, J Lee, SE Shoelson - Arteriosclerosis, thrombosis, and …, 2012 - Am Heart Assoc
Obesity and its comorbidities, including type 2 diabetes mellitus and cardiovascular disease,
are associated with a state of chronic low-grade inflammation that can be detected both …
are associated with a state of chronic low-grade inflammation that can be detected both …
Obesity associated disease risk: the role of inherent differences and location of adipose depots
JH Hill, C Solt, MT Foster - Hormone molecular biology and clinical …, 2018 - degruyter.com
Obesity and associated metabolic co-morbidities are a worldwide public health problem.
Negative health outcomes associated with obesity, however, do not arise from excessive …
Negative health outcomes associated with obesity, however, do not arise from excessive …
An update on the secretory functions of brown, white, and beige adipose tissue: Towards therapeutic applications
Adipose tissue, including white adipose tissue (WAT), brown adipose tissue (BAT), and
beige adipose tissue, is vital in modulating whole-body energy metabolism. While WAT …
beige adipose tissue, is vital in modulating whole-body energy metabolism. While WAT …
The many secret lives of adipocytes: implications for diabetes
PE Scherer - Diabetologia, 2019 - Springer
Adipose tissue remains a cryptic organ. The ubiquitous presence of adipocytes, the different
fat pads in distinct anatomical locations, the many different types of fat, in each case with …
fat pads in distinct anatomical locations, the many different types of fat, in each case with …
[PDF][PDF] Obesity-associated low-grade inflammation in type 2 diabetes mellitus: causes and consequences
MM Van Greevenbroek, CG Schalkwijk, CD Stehouwer - Neth J Med, 2013 - njmonline.nl
The epidemic of overweight and obesity is a major problem because of the plethora of
health and economic issues that it induces. Key among these is the sharply increasing …
health and economic issues that it induces. Key among these is the sharply increasing …
Adipose tissue: between the extremes
A Vegiopoulos, M Rohm, S Herzig - The EMBO journal, 2017 - embopress.org
Adipose tissue represents a critical component in healthy energy homeostasis. It fulfills
important roles in whole‐body lipid handling, serves as the body's major energy storage …
important roles in whole‐body lipid handling, serves as the body's major energy storage …
[HTML][HTML] Targeting white, brown and perivascular adipose tissue in atherosclerosis development
AD van Dam, MR Boon, JFP Berbée… - European journal of …, 2017 - Elsevier
Obesity is a well-established risk factor for atherosclerosis. However, the mechanistic link
between accumulation of adipose tissue and development of atherosclerosis is not clear …
between accumulation of adipose tissue and development of atherosclerosis is not clear …
Rewiring of lipid metabolism in adipose tissue macrophages in obesity: impact on insulin resistance and type 2 diabetes
VD Dahik, E Frisdal, W Le Goff - International journal of molecular …, 2020 - mdpi.com
Obesity and its two major comorbidities, insulin resistance and type 2 diabetes, represent
worldwide health issues whose incidence is predicted to steadily rise in the coming years …
worldwide health issues whose incidence is predicted to steadily rise in the coming years …
The adipose organ: white‐brown adipocyte plasticity and metabolic inflammation
White adipocytes can store energy, whereas brown adipocytes dissipate energy for
thermogenesis. These two cell types with opposing functions are contained in multiple fat …
thermogenesis. These two cell types with opposing functions are contained in multiple fat …
Obesity and the development of type 2 diabetes: the effects of fatty tissue inflammation
DP Schuster - Diabetes, metabolic syndrome and obesity: targets …, 2010 - Taylor & Francis
Obesity is a worldwide epidemic with multiple obesity-associated health problems including
type 2 diabetes, hypertension, and cardiovascular disease. Adipose tissue serves as a fuel …
type 2 diabetes, hypertension, and cardiovascular disease. Adipose tissue serves as a fuel …