Integration of GC–MS and LC–MS for untargeted metabolomics profiling
Recently, metabolomics analyses have become increasingly common in the general
scientific community as it is applied in several researches relating to diseases diagnosis …
scientific community as it is applied in several researches relating to diseases diagnosis …
[图书][B] Metabolomics: methods and protocols
W Weckwerth - 2008 - books.google.com
Metabolomics: Methods and Protocols examines the state-of-the-art in metabolomic
analysis. Leading researchers in the field present protocols for the application of …
analysis. Leading researchers in the field present protocols for the application of …
MetaboliteDetector: comprehensive analysis tool for targeted and nontargeted GC/MS based metabolome analysis
We have developed a new software, MetaboliteDetector, for the efficient and automatic
analysis of GC/MS-based metabolomics data. Starting with raw MS data, the program …
analysis of GC/MS-based metabolomics data. Starting with raw MS data, the program …
Development and performance of a gas chromatography− time-of-flight mass spectrometry analysis for large-scale nontargeted metabolomic studies of human serum
P Begley, S Francis-McIntyre, WB Dunn… - Analytical …, 2009 - ACS Publications
A method for the preparation and GC− TOF-MS analysis of human serum samples has been
developed and evaluated for application in long-term metabolomic studies. Serum samples …
developed and evaluated for application in long-term metabolomic studies. Serum samples …
Quantitative metabolomics based on gas chromatography mass spectrometry: status and perspectives
MM Koek, RH Jellema, J van der Greef, AC Tas… - Metabolomics, 2011 - Springer
Metabolomics involves the unbiased quantitative and qualitative analysis of the complete set
of metabolites present in cells, body fluids and tissues (the metabolome). By analyzing …
of metabolites present in cells, body fluids and tissues (the metabolome). By analyzing …
TargetSearch-a Bioconductor package for the efficient preprocessing of GC-MS metabolite profiling data
A Cuadros-Inostroza, C Caldana, H Redestig… - BMC …, 2009 - Springer
Background Metabolite profiling, the simultaneous quantification of multiple metabolites in
an experiment, is becoming increasingly popular, particularly with the rise of systems-level …
an experiment, is becoming increasingly popular, particularly with the rise of systems-level …
Improving the quality of biomarker candidates in untargeted metabolomics via peak table-based alignment of comprehensive two-dimensional gas chromatography …
The potential of high-resolution analytical technologies like GC× GC/TOF MS in untargeted
metabolomics and biomarker discovery has been limited by the development of fully …
metabolomics and biomarker discovery has been limited by the development of fully …
Data processing for mass spectrometry-based metabolomics
M Katajamaa, M Orešič - Journal of chromatography A, 2007 - Elsevier
Modern analytical technologies afford comprehensive and quantitative investigation of a
multitude of different metabolites. Typical metabolomic experiments can therefore produce …
multitude of different metabolites. Typical metabolomic experiments can therefore produce …
Mass appeal: metabolite identification in mass spectrometry-focused untargeted metabolomics
Metabolomics has advanced significantly in the past 10 years with important developments
related to hardware, software and methodologies and an increasing complexity of …
related to hardware, software and methodologies and an increasing complexity of …
[HTML][HTML] Optimizing 2D gas chromatography mass spectrometry for robust tissue, serum and urine metabolite profiling
Z Yu, H Huang, A Reim, PD Charles, A Northage… - Talanta, 2017 - Elsevier
Two-dimensional gas chromatography mass spectrometry (GCxGC-MS) is utilized to an
increasing extent in biomedical metabolomics. Here, we established and adapted …
increasing extent in biomedical metabolomics. Here, we established and adapted …