m6A‐mediated regulation of PBX1‐GCH1 axis promotes gastric cancer proliferation and metastasis by elevating tetrahydrobiopterin levels
Y Liu, E Zhai, J Chen, Y Qian, R Zhao… - Cancer …, 2022 - Wiley Online Library
Abstract Background Methyltransferase 3 (METTL3)‐mediated N6‐methyladenosine (m6A)
RNA modification has been demonstrated to be a potential factor in promoting gastric cancer …
RNA modification has been demonstrated to be a potential factor in promoting gastric cancer …
METTL16 promotes cell proliferation by up‐regulating cyclin D1 expression in gastric cancer
XK Wang, YW Zhang, CM Wang, B Li… - Journal of cellular …, 2021 - Wiley Online Library
Abstract N6‐methyladenosine (m6A) is a well‐known modification of RNA. However, as a
key m6A methyltransferase, METTL16 has not been thoroughly studied in gastric cancer …
key m6A methyltransferase, METTL16 has not been thoroughly studied in gastric cancer …
[HTML][HTML] METTL3 promotes the proliferation and mobility of gastric cancer cells
S Lin, J Liu, W Jiang, P Wang, C Sun, X Wang… - Open …, 2019 - degruyter.com
Abstract Methyltransferase-like 3 (METTL3) was originally known to be responsible for N6-
methyladenosine (m6A) modification of mRNA. Recent studies have found that METTL3 …
methyladenosine (m6A) modification of mRNA. Recent studies have found that METTL3 …
The m6A methyltransferase METTL14 inhibits the proliferation, migration, and invasion of gastric cancer by regulating the PI3K/AKT/mTOR signaling pathway
X Liu, M Xiao, L Zhang, L Li, G Zhu… - Journal of clinical …, 2021 - Wiley Online Library
Abstract Background N6‐methyladenosine (m6A) modification may participate in the
regulation of occurrence and development of tumors. However, the m6A level and the …
regulation of occurrence and development of tumors. However, the m6A level and the …
[HTML][HTML] METTL3 promotes the progression of gastric cancer via targeting the MYC pathway
DD Yang, ZH Chen, K Yu, JH Lu, QN Wu… - Frontiers in …, 2020 - frontiersin.org
Methyltransferase-like 3 (METTL3), a major component of the N6-methyladenosine (m6A)
methyltransferase complex, has been suggested to function as an oncogene in several …
methyltransferase complex, has been suggested to function as an oncogene in several …
[HTML][HTML] The m6A methyltransferase METTL14-mediated N6-methyladenosine modification of PTEN mRNA inhibits tumor growth and metastasis in stomach …
Q Yao, L He, X Gao, N Tang, L Lin, X Yu… - Frontiers in …, 2021 - frontiersin.org
Background Stomach adenocarcinoma (STAD) is a common reason for tumor-related
fatalities globally, as it results in distant metastasis. Methyltransferase-like 14 (METTL14), a …
fatalities globally, as it results in distant metastasis. Methyltransferase-like 14 (METTL14), a …
[HTML][HTML] METTL3-mediated N6-methyladenosine modification is critical for epithelial-mesenchymal transition and metastasis of gastric cancer
B Yue, C Song, L Yang, R Cui, X Cheng, Z Zhang… - Molecular cancer, 2019 - Springer
Background As one of the most frequent chemical modifications in eukaryotic mRNAs, N6-
methyladenosine (m6A) modification exerts important effects on mRNA stability, splicing …
methyladenosine (m6A) modification exerts important effects on mRNA stability, splicing …
METTL3-mediated m6A modification of HDGF mRNA promotes gastric cancer progression and has prognostic significance
Q Wang, C Chen, Q Ding, Y Zhao, Z Wang, J Chen… - Gut, 2020 - gut.bmj.com
Objective N6-methyladenosine (m6A) RNA methylation and its associated methyltransferase
METTL3 are involved in tumour initiation and progression via the regulation of RNA function …
METTL3 are involved in tumour initiation and progression via the regulation of RNA function …
[HTML][HTML] The m6A methyltransferase METTL3-mediated N6-methyladenosine modification of DEK mRNA to promote gastric cancer cell growth and metastasis
HM Zhang, FF Qi, J Wang, YY Duan, LL Zhao… - International Journal of …, 2022 - mdpi.com
Gastric cancer (GC) is the fifth most common cancer and the third deadliest cancer in the
world, and the occurrence and development of GC are influenced by epigenetics …
world, and the occurrence and development of GC are influenced by epigenetics …
[HTML][HTML] Knockdown of RNA N6-methyladenosine methyltransferase METTL3 represses Warburg effect in colorectal cancer via regulating HIF-1α
Z Yang, Y Quan, Y Chen, Y Huang, R Huang… - … and Targeted Therapy, 2021 - nature.com
Colorectal cancer (CRC) is an important digestive tract tumor with high malignancy. Nearly
one million people suffer from CRC every year with a mortality rate of 33%. Therefore, it is …
one million people suffer from CRC every year with a mortality rate of 33%. Therefore, it is …