Overcoming obstacles in microRNA delivery towards improved cancer therapy
D Ben-Shushan, E Markovsky, H Gibori… - Drug delivery and …, 2014 - Springer
MicroRNAs (miRNAs) are small noncoding RNAs found to govern nearly every biological
process. They frequently acquire a gain or a loss of function in cancer, hence playing a …
process. They frequently acquire a gain or a loss of function in cancer, hence playing a …
Nanocarriers for microRNA delivery in cancer medicine
I Fernandez-Piñeiro, I Badiola, A Sanchez - Biotechnology advances, 2017 - Elsevier
The number of deaths caused by cancer is expected to increase partly due to the lack of
selectivity and undesirable systemic effects of current treatments. Advances in the …
selectivity and undesirable systemic effects of current treatments. Advances in the …
A comprehensive review of cancer MicroRNA therapeutic delivery strategies
A Forterre, H Komuro, S Aminova, M Harada - Cancers, 2020 - mdpi.com
In the field of molecular oncology, microRNAs (miRNAs) and their role in regulating
physiological processes and cancer pathogenesis have been a revolutionary discovery over …
physiological processes and cancer pathogenesis have been a revolutionary discovery over …
MicroRNAs and their big therapeutic impacts: delivery strategies for cancer intervention
C Holjencin, A Jakymiw - Cells, 2022 - mdpi.com
Three decades have passed from the initial discovery of a microRNA (miRNA) in
Caenorhabditis elegans to our current understanding that miRNAs play essential roles in …
Caenorhabditis elegans to our current understanding that miRNAs play essential roles in …
Non-viral nanocarriers for intracellular delivery of microRNA therapeutics
Z Bai, J Wei, C Yu, X Han, X Qin, C Zhang… - Journal of Materials …, 2019 - pubs.rsc.org
MicroRNAs are small regulatory noncoding RNAs that regulate various biological processes
associated with neurological disorders, cardiovascular diseases, cancer and viral infection …
associated with neurological disorders, cardiovascular diseases, cancer and viral infection …
Therapeutic microRNA delivery strategies with special emphasis on cancer therapy and tumorigenesis: current trends and future challenges
C Chakraborty, ZH Wen… - Current drug …, 2016 - ingentaconnect.com
Background: Over the decade, miRNAs are the most important molecules for the
biopharmaceutical industry due to their relation with several human diseases. Presently, the …
biopharmaceutical industry due to their relation with several human diseases. Presently, the …
Lipid nanoparticles to deliver miRNA in cancer
MicroRNAs (miRNAs) are a class of post-transcriptional gene expression modulators. In the
past two decades, over 1500 human miRNAs were discovered. These small non-coding …
past two decades, over 1500 human miRNAs were discovered. These small non-coding …
miRNA delivery by nanosystems: state of the art and perspectives
MicroRNAs (miRNAs) are short (~ 21–23 nucleotides), non-coding endogenous RNA
molecules that modulate gene expression at the post-transcriptional level via the …
molecules that modulate gene expression at the post-transcriptional level via the …
Non-viral based miR delivery and recent developments
AE Labatut, G Mattheolabakis - European Journal of Pharmaceutics and …, 2018 - Elsevier
Abstract miRNAs are promising therapeutic targets or tools for the treatment of numerous
diseases, with most prominently, cancer. The inherent capacity of these short nucleic acids …
diseases, with most prominently, cancer. The inherent capacity of these short nucleic acids …
Delivery of therapeutic miRNA using polymer-based formulation
MicroRNAs (miRNAs) are short non-coding RNAs that play important roles in many cellular
processes such as development, proliferation, differentiation, and apoptosis. For this reason …
processes such as development, proliferation, differentiation, and apoptosis. For this reason …