Natural products in drug discovery–creating a new vision
GA Cordell - Phytochemistry Reviews, 2002 - Springer
Abstract “If only they had chosen to develop natural product drugs in a sustainable manner
at the turn of the century”. In 2050, when the Earth has a population of at least 9 billion, will …
at the turn of the century”. In 2050, when the Earth has a population of at least 9 billion, will …
[HTML][HTML] Plant-derived natural products for drug discovery: current approaches and prospects
N Nasim, IS Sandeep, S Mohanty - The Nucleus, 2022 - Springer
Nature has abundant source of drugs that need to be identified/purified for use as essential
biologics, either individually or in combination in the modern medical field. These drugs are …
biologics, either individually or in combination in the modern medical field. These drugs are …
[PDF][PDF] 3.08—Natural products drug discovery
G Appendino, G Fontana… - … Natural Products II …, 2010 - researchgate.net
Over the past two decades natural products drug discovery has been increasingly de-
emphasized by pharmaceutical companies. Although heralded on the verge of a comeback …
emphasized by pharmaceutical companies. Although heralded on the verge of a comeback …
[图书][B] Plant bioactives and drug discovery: principles, practice, and perspectives
V Cechinel-Filho - 2012 - books.google.com
An in-depth exploration of the applications of plant bioactive metabolites in drug research
and development Highlighting the complexity and applications of plant bioactive metabolites …
and development Highlighting the complexity and applications of plant bioactive metabolites …
Natural product drug discovery and development
GM Cragg, MR Boyd, R Khanna… - … in human health …, 1999 - books.google.com
Over the ages, humans have relied on nature for their basic needs for the production of
foodstuffs, shelters, clothing, means of transportation, fertilizers, flavors and fragrances, and …
foodstuffs, shelters, clothing, means of transportation, fertilizers, flavors and fragrances, and …
Discovery, development, and regulation of natural products
Natural products have historically been an extremely productive source for new medicines in
all cultures and continue to deliver a great variety of structural templates for drug discovery …
all cultures and continue to deliver a great variety of structural templates for drug discovery …
Natural products in drug discovery: impacts and opportunities—an assessment
G Brahmachari - … natural products: opportunities and challenges in …, 2012 - World Scientific
Nature stands as an inexhaustible source of novel chemotypes and pharmacophores, and
has been a source of medicinal agents for thousands of years, and an impressive number of …
has been a source of medicinal agents for thousands of years, and an impressive number of …
Medicines from nature: are natural products still relevant to drug discovery?
AL Harvey - Trends in Pharmacological Sciences, 1999 - cell.com
Historically, most drugs have been derived from natural products, but there has been a shift
away from their use with the increasing predominance of molecular approaches to drug …
away from their use with the increasing predominance of molecular approaches to drug …
[HTML][HTML] Unraveling plant natural chemical diversity for drug discovery purposes
E Lautie, O Russo, P Ducrot, JA Boutin - Frontiers in pharmacology, 2020 - frontiersin.org
The screening and testing of extracts against a variety of pharmacological targets in order to
benefit from the immense natural chemical diversity is a concern in many laboratories …
benefit from the immense natural chemical diversity is a concern in many laboratories …
The role of natural product chemistry in drug discovery
MS Butler - Journal of natural products, 2004 - ACS Publications
Although traditionally natural products have played an important role in drug discovery, in
the past few years most Big Pharma companies have either terminated or considerably …
the past few years most Big Pharma companies have either terminated or considerably …