Obesity has been associated with an increased risk of colorectal neoplasia, but the
mechanisms of this potential association have not been elucidated. We hypothesized that …

Purpose Leptin and adiponectin are adipokines which have been commonly implicated in
carcinogenesis. As such, many studies have investigated the association of circulating leptin …

Adipokines are adipocyte-secreted hormones that may mediate the etiologic link between
obesity and colorectal cancer; however, the evidence from large prospective studies is …

Obesity, an established risk factor for colorectal cancer, is characterized by the accumulation
of excessive adipose tissue, which is the source of a variety of biologically active …

Adiponectin—an adipose tissue-derived protein—may provide a molecular link between
obesity and colorectal cancer (CRC), but evidence from large prospective studies is limited …

Adiponectin is an adipocyte‐derived protein with an insulin‐sensitizing action. Circulating
levels of adiponectin are inversely correlated with obesity, especially abdominal obesity …

AIM: To investigate the association between adiponectin levels and risk of colorectal
adenoma and cancer (early and advanced). METHODS: A cross-sectional study in a cohort …

Background: Adiponectin is an insulin-sensitizing hormone secreted by adipocytes. Levels
of adiponectin are inversely associated with adiposity and insulin resistance. Because both …

Purpose: Colorectal carcinogenesis is thought to be related to abdominal obesity and insulin
resistance. To investigate whether visceral fat accumulation contributes to colorectal …

Colorectal cancer is an obesity-related malignancy. Adiponectin is an adipokine produced
exclusively by adipose tissue, and its concentration in the serum is reduced in obesity. A low …