Medications in pregnancy and lactation

DE McCarter-Spaulding - MCN: The American Journal of Maternal …, 2005 - journals.lww.com
The issue of medication use during pregnancy is of concern because the physiology of
pregnancy affects the pharmokinetics of medications used, and certain medications can …

Pharmacological management of hypertension in pregnancy

TR Easterling - Seminars in perinatology, 2014 - Elsevier
Hypertension in pregnancy remains a significant public health problem. Pharmacological
management of blood pressure in pregnancy is impacted by changes in maternal drug …

Pharmacokinetics in pregnancy and placental drug transfer.

F Reynolds, C Knott - Oxford reviews of reproductive biology, 1989 - europepmc.org
Total body water increases in pregnancy and while the uterus, placenta, fetus, and amniotic
fluid constitute part of this increase, the largest component is in the extracellular water. Fat …

Epidemiology of drugs taken by pregnant women: drugs that may affect the fetus adversely

JO Forfar, MM Nelson - Clinical Pharmacology & Therapeutics, 1973 - Wiley Online Library
The epidemiology of drug consumption during pregnancy has been studied retrospectively
in 911 randomly selected mothers. The drugs used, the proportions of pregnant women …

Physiologically based pharmacokinetic modeling in pregnancy: a systematic review of published models

A Dallmann, M Pfister, J van den Anker… - Clinical …, 2018 - Wiley Online Library
During recent years there has been a surge in developing and applying physiologically
based pharmacokinetic (PBPK) models in pregnant women to better understand and predict …