The cellular effects of purines and pyrimidines are mediated through an extended
superfamily of purinoceptors, which include metabotropic P1 (adenosine) receptors, and P2 …

Membrane receptors that are activated by the purine nucleoside adenosine (adenosine
receptors) or by purine or pyrimidine nucleotides (P2Y and P2X receptors) transduce …

A brief account of the early history of extracellular signalling by ATP will be followed by a
summary of the current subclassification of receptors for purines and pyrimidines. On the …

Extracellular purines (adenosine, ADP, and ATP) and pyrimidines (UDP and UTP) are
important signaling molecules that mediate diverse biological effects via cellsurface …

There has been an exponential growth in interest n purinoceptors since the potent effects of
purines were first reported in 1929 and purinoceptors defined in 1978. A distinction between …

This is an overview of the fast-moving field of purinergic signalling through adenosine and
ATP receptors. Authors are the leading authorities in their fields Subject matter is important …

The term purinergic receptor (or purinoceptor) was first introduced to describe classes of
membrane receptors that, when activated by either neurally released ATP (P2 purinoceptor) …

The purine nucleoside adenosine and the purine nucleotide ATP play different roles in the
nervous system. Adenosine acts on a family of G protein coupled receptors, collectively …

In the last decade, the field of purinergic pharmacology has continued to grow as the
complexity of the receptor families and the various enzymes involved in purine metabolism …

Adenine-based purines, such as adenosine and ATP, are ubiquitous molecules that, in
addition to their roles in metabolism, act as modulators of neurotransmitter release through …