Background: The tumor suppressor gene p53 is a nuclear protein which plays a key role in
tumor progression by regulating DNA repair, cell division and apoptosis. One major function …

The expression of p21 and p53 proteins was analyzed by immunohistochemistry in 256
patients with advanced gastric cancer. The results showed that strong, weak and negative …

The prognostic value of overexpression of the p53-encoded protein was evaluated in 242
patients with gastric cancer. Formalin-fixed paraffin-embedded specimens of gastric …

We studied p53 and p21 expression simultaneously in gastric carcinoma tissues to
investigate the clinical significance of p53-p21 pathway in this disease. One hundred sixty …

Background The variability of prognosis within a pathological stage of gastric cancer (GC) at
presentation, underscores the need for specific biological markers to identify subgroups of …

Background: P53-tumor suppressor gene has an essential role in controlling cell cycle and
initiating carcinogenesis. In the case of gastric cancer, the role of p53-protein accumulation …

The prognostic value of the immunohistochemical expression of p53 protein, proliferating-
cell nuclear antigen (PCNA) and Ki-67 antigen was evaluated in a series of 116 stage I–II …

Mutations in the p53 gene, one of the most common genetic alterations in human cancer,
are implicated in tumorigenesis and tumour progression. Although p53 protein expression …

A study was carried out to assess whether p53 expression is related to tumour type, grade or
pathological characteristics, or to prognosis, in gastric cancer. Immunohistochemical studies …

For evaluation of the prognostic relevance ofp53 expression in gastric cancer,
theimmunohistochemical tissue status of 133 primary gastriccancer patients was …