Objective: We sought to develop a comprehensive program for clinical genetic testing in a
large group of extended families with multiple endocrine neoplasia type 1 (MEN 1), with the …

Multiple endocrine neoplasia type 1 (MEN1) is a classic hereditary tumor syndrome
characterized by a genetic predisposition to develop a variety of neuroendocrine neoplasias …

Objective: To review and assess the role of MEN1 mutational analysis in clinical practice.
Methods: Articles relevant to MEN1 mutation testing and screening were reviewed. Results …

Purpose Multiple endocrine neoplasia type 1 (MEN1) is caused by germline inactivating
mutations of the MEN1 gene. Currently, no direct genotype–phenotype correlation is …

Pancreatic endocrine tumors (PETs) may be sporadic or inherited in the multiple endocrine
neoplasia type 1 (MEN-1) syndrome. The inherited form is caused by mutations of the MEN …

Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant syndrome
predisposing to tumors of the parathyroid, endocrine pancreas, anterior pituitary, adrenal …

Hypothesis Multiple endocrine neoplasia type 1 (MEN 1) syndrome is an autosomal
dominant disorder caused by germline mutations in theMEN1gene and characterized by …

Multiple endocrine neoplasia syndrome type 1 (MEN1) syndrome has benefited from the
identification of the gene whose mutations account for the genetic susceptibility to develop …

Background Multiple endocrine neoplasia type 1 (MEN 1) is an autosomal, dominantly
inherited cancer syndrome, with tumours in various endocrine glands. In 1997 the …

Multiple endocrine neoplasia type 1 (MEN1) consists of benign, and sometimes malignant,
tumors (often multiple in a tissue) of the parathyroids, enteropancreatic neuroendocrine …