Biology of cancer; from cellular cancerogenesis to supracellular evolution of malignant phenotype

IG Motofei - Cancer investigation, 2018 - Taylor & Francis
Until now cancerogenesis has been studied in close relation with the corresponding
malignant phenotype. Such unified approach defines cancer as uncontrolled cellular …

Biology of cancer; from cellular and molecular mechanisms to developmental processes and adaptation

IG Motofei - Seminars in Cancer Biology, 2022 - Elsevier
Cancer research has been largely focused on the cellular and molecular levels of
investigation. Recent data show that not only the cell but also the extracellular matrix plays a …

Biology of cancer: Understanding the supracellular control of mitosis in physiological processes and malignancy

IG Motofei - Seminars in Cancer Biology, 2023 - Elsevier
Malignancy is a serious life-threatening disease, so various therapeutic strategies have
been developed over time. Unfortunately, the treatments currently in use cannot effectively …

[引用][C] Carcinogenesis—cellular evolution as a unifying thread: Presidential address

E Farber - Cancer Research, 1973 - AACR
Dr. Creech, fellow members, and guests, I would like to take this opportunity to thank you for
the honor of being your president for the past year. It has been a year of mixed blessings for …

Cancer: shift of the paradigm

AV Lichtenstein - Medical hypotheses, 2008 - Elsevier
Cancer is usually considered to be a by-product of design limitations of a multicellular
organism and its intrinsic fallibility. However, recent data prompt a revision of some …

The three steps to cancer: a new concept of cancerigenesis

MM Melicow - Journal of Theoretical Biology, 1982 - Elsevier
A new theory of carcinogenesis is presented. It is based on the premise that the initial step in
the development of cancer is injury by a carcinogen of the coding units in the specialized …

The nature of cancer: morphogenesis and progressive (self)-disorganization in neoplastic development and progression

WH Clark - Acta Oncologica, 1995 - Taylor & Francis
The aberrant forms of life, neoplasia and cancer, are discussed under the events at the
beginning of neoplasia and under five classes of neoplastic lesions. The lesional classes …

The mechanisms of neoplastic transformation

L Luzzatto - European Journal of Cancer, 2001 - ejcancer.com
Historically, the contemporary understanding of tumours developed hand in hand with
Virchow's notion that the cell was the basic element of many diseases. Indeed, classical …

The role of cell differentiation in controlling cell multiplication and cancer

KH Von Wangenheim, HP Peterson - Journal of cancer research and …, 2008 - Springer
It has been suggested that cancer ought to be regarded as a disease of cell differentiation. In
multicellular organisms, indeed, the control of cell multiplication is linked to cell …

[图书][B] Cell growth

C Nicolini - 2013 - books.google.com
During October 18-31, 1980, the first course of the International School of Pure and Applied
Biostructure, a NATO Advanced Study Institute was held at the" Ettore Majorana Center for …