Cellular and molecular electrophysiology of atrial fibrillation initiation, maintenance, and progression
Atrial fibrillation (AF) is the most common clinically relevant arrhythmia and is associated
with increased morbidity and mortality. The incidence of AF is expected to continue to rise …
with increased morbidity and mortality. The incidence of AF is expected to continue to rise …
Therapeutic implications of atrial fibrillation mechanisms: can mechanistic insights be used to improve AF management?
S Nattel - Cardiovascular research, 2002 - academic.oup.com
Atrial fibrillation (AF) is a very common clinical problem, and presently available treatment
options are suboptimal. A tremendous amount has been learned over the past 10 years …
options are suboptimal. A tremendous amount has been learned over the past 10 years …
Molecular basis of atrial fibrillation pathophysiology and therapy: a translational perspective
Atrial fibrillation (AF) is a highly prevalent arrhythmia, with substantial associated morbidity
and mortality. There have been significant management advances over the past 2 decades …
and mortality. There have been significant management advances over the past 2 decades …
Translational challenges in atrial fibrillation
Atrial fibrillation (AF) is the most common sustained heart rhythm disorder and is associated
with substantial morbidity and mortality. Current treatment options for AF have significant …
with substantial morbidity and mortality. Current treatment options for AF have significant …
Mechanisms of atrial fibrillation
RS Wijesurendra, B Casadei - Heart, 2019 - heart.bmj.com
Atrial fibrillation (AF) is the most common sustained arrhythmia, currently affecting over 33
million individuals worldwide, and its prevalence is expected to more than double over the …
million individuals worldwide, and its prevalence is expected to more than double over the …
The value of basic research insights into atrial fibrillation mechanisms as a guide to therapeutic innovation: a critical analysis
Atrial fibrillation (AF) is an extremely common clinical problem associated with increased
morbidity and mortality. Current antiarrhythmic options include pharmacological, ablation …
morbidity and mortality. Current antiarrhythmic options include pharmacological, ablation …
Basic mechanisms of atrial fibrillation—very new insights into very old ideas
▪ Abstract Atrial fibrillation (AF) was recognized and studied extensively in the early twentieth
century, but many fundamental aspects of the arrhythmia were poorly understood until quite …
century, but many fundamental aspects of the arrhythmia were poorly understood until quite …
The multidimensional role of calcium in atrial fibrillation pathophysiology: mechanistic insights and therapeutic opportunities
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, and its prevalence is
increasing with the ageing of the population. Presently available treatment options are far …
increasing with the ageing of the population. Presently available treatment options are far …
[HTML][HTML] Atrial fibrillation: mechanisms, therapeutics, and future directions
J Pellman, F Sheikh - Comprehensive Physiology, 2015 - ncbi.nlm.nih.gov
Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia, affecting 1% to 2% of the
general population. It is characterized by rapid and disorganized atrial activation leading to …
general population. It is characterized by rapid and disorganized atrial activation leading to …
Electrophysiological and molecular mechanisms of paroxysmal atrial fibrillation
Atrial fibrillation (AF) is an extremely prevalent arrhythmia that presents a wide range of
therapeutic challenges. AF usually begins in a self-terminating paroxysmal form (pAF). With …
therapeutic challenges. AF usually begins in a self-terminating paroxysmal form (pAF). With …