Methylation of cytosines at CpG sites is a common epigenetic DNA modification that can be
measured by a large number of methods, now even in a genome-wide manner for hundreds …

Epigenetic studies are commonly conducted on DNA from tissue samples. However, tissues
are ensembles of cells that may each have their own epigenetic profile, and therefore inter …

DNA methylation is one of several epigenetic mechanisms that contribute to the regulation of
gene expression; however, the extent to which methylation of CpG dinucleotides correlates …

DNA methylation is a key epigenetic modification which, in mammals, occurs mainly at CpG
dinucleotides. Most of the CpG methylation in the genome is found in repetitive regions, rich …

DNA methylation is among the best studied epigenetic modifications and is essential to
mammalian development. Although the methylation status of most CpG dinucleotides in the …

Genome wide analysis of DNA methylation provides important information in a variety of
diseases, including cancer. Here, we describe a simple method, Digital Restriction Enzyme …

Using a methylated-DNA enrichment technique (methylated CpG island recovery assay,
MIRA) in combination with whole-genome tiling arrays, we have characterized by MIRA-chip …

DNA methylation of CpGs located in two types of repetitive elements—LINE1 (L1) and Alu—
is used to assess “global” changes in DNA methylation in studies of human disease and …

DNA methylation has been viewed as a stable component of the epigenome, which is
established during development and fixed thereafter. We show here using nearest neighbor …

Cytosine-5 methylation within CpG dinucleotides is a potentially important mechanism of
epigenetic influence on human traits and disease. In addition to influences of age and …