Heparan sulfate (HS) is present on the surface of endothelial and surrounding tissues in
large quantities. It plays important roles in regulating numerous functions of the blood vessel …

Heparan sulfate (HS) is a highly sulfated polysaccharide playing essential physiological and
pathophysiological roles in the animal kingdom. Heparin, a highly sulfated form of HS, is a …

Heparan sulfate (HS) polysaccharides interact with numerous proteins at the cell surface
and orchestrate many different biological functions. Though many functions of HS are well …

The glycosaminoglycan heparan sulfate (HS), is expressed on the surface of virtually all
mammalian cells and is implicated in many crucial biological activities. The activities of HS …

Heparan sulfate carries a wide range of biological activities, regulating blood coagulation,
cell differentiation, and inflammatory responses. The sulfation patterns of the polysaccharide …

The sulfated glycosaminoglycans, heparan sulfate and heparin, are increasingly implicated
in cell‐biological processes such as cytokine action, cell adhesion, and regulation of …

The role of heparan sulfate (HS) in regulating blood coagulation has a wide range of clinical
implications. In this study, we investigated the role of 3-O-sulfotransferase isoform 5 (3-OST …

Publisher Summary This chapter discusses the structural aspects and structure–activity
relationships of heparin/heparan sulfate (HS). The molecular mechanism behind the …

Heparan sulfate (HS) is a linear polysaccharide composed of 50–200 glucosamine and
uronic acid (glucuronic acid or iduronic acid) disaccharide repeats with epimerization and …

Heparan sulfate (HS) is a sulfated polysaccharide present on cell surfaces and in the
extracellular matrix. Accumulating evidence shows that HS plays key roles in many …