Metabolic dysfunctions in amyotrophic lateral sclerosis pathogenesis and potential metabolic treatments
TW Tefera, K Borges - Frontiers in neuroscience, 2017 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease primarily
characterized by loss of motor neurons in brain and spinal cord. The death of motor neurons …
characterized by loss of motor neurons in brain and spinal cord. The death of motor neurons …
[HTML][HTML] Altered bioenergetics and metabolic homeostasis in amyotrophic lateral sclerosis
AT Nelson, D Trotti - Neurotherapeutics, 2022 - Elsevier
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease that
primarily affects motor neurons and causes muscle atrophy, paralysis, and death. While a …
primarily affects motor neurons and causes muscle atrophy, paralysis, and death. While a …
Energy metabolism in ALS: an underappreciated opportunity?
Amyotrophic lateral sclerosis (ALS) is a relentlessly progressive and fatal
neurodegenerative disorder that primarily affects motor neurons. Despite our increased …
neurodegenerative disorder that primarily affects motor neurons. Despite our increased …
Understanding and managing metabolic dysfunction in Amyotrophic Lateral Sclerosis
H Blasco, D Lanznaster, C Veyrat-Durebex… - Expert Review of …, 2020 - Taylor & Francis
ABSTRACT Introduction Amyotrophic Lateral Sclerosis (ALS) is a fatal motor neuron disease
that leads to death after a median survival of 36 months. The development of an effective …
that leads to death after a median survival of 36 months. The development of an effective …
CNS glucose metabolism in Amyotrophic Lateral Sclerosis: a therapeutic target?
Amyotrophic lateral sclerosis (ALS) is a fatal progressive neurodegenerative disorder
primarily characterized by selective degeneration of both the upper motor neurons in the …
primarily characterized by selective degeneration of both the upper motor neurons in the …
Altered metabolic homeostasis in amyotrophic lateral sclerosis: mechanisms of energy imbalance and contribution to disease progression
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by
the death of motor neurones, which leads to paralysis and death in an average of 3 years …
the death of motor neurones, which leads to paralysis and death in an average of 3 years …
Nutritional and metabolic factors in amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a complex neurodegenerative disease that is
classically thought to impact the motor system. Over the past 20 years, research has started …
classically thought to impact the motor system. Over the past 20 years, research has started …
Metabolic dysregulation in amyotrophic lateral sclerosis: challenges and opportunities
A Joardar, E Manzo, DC Zarnescu - Current genetic medicine reports, 2017 - Springer
Abstract Purpose of Review Amyotrophic lateral sclerosis (ALS) is a progressive
neurodegenerative disease for which there is no cure and treatments are at best palliative …
neurodegenerative disease for which there is no cure and treatments are at best palliative …
Evidence of metabolic dysfunction in amyotrophic lateral sclerosis (ALS) patients and animal models
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that affects motor
neurons, leading to muscle weakness, paralysis, and eventual death. Research from the …
neurons, leading to muscle weakness, paralysis, and eventual death. Research from the …
[HTML][HTML] The interplay between metabolic homeostasis and neurodegeneration: insights into the neurometabolic nature of amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a fatal, neurodegenerative disease that is
characterized by the selective degeneration of upper motor neurons and lower spinal motor …
characterized by the selective degeneration of upper motor neurons and lower spinal motor …