Effects of ambient PM2.5 on pathological injury, inflammation, oxidative stress, metabolic enzyme activity, and expression of c-fos and c-jun in lungs of rats

R Li, X Kou, L Xie, F Cheng, H Geng - Environmental Science and …, 2015 - Springer
Abstract Fine particulate matter (PM 2.5) exposure is associated with morbidity and mortality
induced by respiratory diseases and increases the lung cancer risk. However, the …

Effect of PM2. 5 environmental pollution on rat lung

B Yang, J Guo, C Xiao - Environmental Science and Pollution Research, 2018 - Springer
Particulate matter smaller than 2.5 μm (PM2. 5) is a continuing challenge to pulmonary
health. Here, we investigated the mechanisms involved in PM2. 5 exposure-induced acute …

Exposure to fine particulate matter induces self-recovery and susceptibility of oxidative stress and inflammation in rat lungs

H Ren, J Lu, J Ning, X Su, Y Tong, J Chen… - … Science and Pollution …, 2020 - Springer
PM 2.5 induces pulmonary inflammation via oxidative stress, and this role in the lungs is
widely accepted, but studies on whether oxidative stress and inflammation can self-recover …

Rat lung response to ozone and fine particulate matter (PM2.5) exposures

G Wang, J Zhao, R Jiang, W Song - Environmental toxicology, 2015 - Wiley Online Library
Exposure to different ambient pollutants maybe more toxic to lung than exposure to a single
pollutant. In this study, we discussed the inflammation and oxidative stress responses of rat …

[HTML][HTML] The influence of PM2. 5 on lung injury and cytokines in mice

J Yang, Y Chen, Z Yu, H Ding… - Experimental and …, 2019 - spandidos-publications.com
Exposure to particulate matter≤ 2.5 µm in diameter (PM2. 5) profoundly affects human
health. However, the role of PM2. 5 on lung injury and cytokine levels in mice is currently …

PM2. 5‐induced lung inflammation in mice: Differences of inflammatory response in macrophages and type II alveolar cells

M He, T Ichinose, S Yoshida, T Ito, C He… - Journal of Applied …, 2017 - Wiley Online Library
Abstract Particulate matter 2.5 (< PM2. 5 μm) leads to chronic obstructive pulmonary
disease. In this study, biomarkers related to inflammation and oxidative stress in vitro and in …

PM2. 5-induced alteration of DNA methylation and RNA-transcription are associated with inflammatory response and lung injury

Y Shi, T Zhao, X Yang, B Sun, Y Li, J Duan… - Science of the total …, 2019 - Elsevier
The mechanisms of systemic pulmonary inflammation and toxicity of fine particulate matter
(PM 2.5) exposure remains unclear. The current study investigated the inflammatory …

Pro‐inflammatory response and oxidative stress induced by specific components in ambient particulate matter in human bronchial epithelial cells

L Yang, G Liu, Z Lin, Y Wang, H He, T Liu… - Environmental …, 2016 - Wiley Online Library
Previous studies have shown that biological effect of particulate matter (PM2. 5) is involved
in including chemical composition and mass concentration, but the precise components and …

[HTML][HTML] Cytotoxicity induced by fine particulate matter (PM2.5) via mitochondria-mediated apoptosis pathway in rat alveolar macrophages

H Wei, W Yuan, H Yu, H Geng - Environmental Science and Pollution …, 2021 - Springer
Although positive associations exist between ambient particulate matter (PM 2.5; diameter≤
2.5 μm) and the morbidity and mortality rates for respiratory diseases, the biological …

[HTML][HTML] The effect of exposure time and concentration of airborne PM2. 5 on lung injury in mice: A transcriptome analysis

H Wang, X Shen, J Liu, C Wu, J Gao, Z Zhang, F Zhang… - Redox biology, 2019 - Elsevier
The association between airborne fine particulate matter (PM 2.5) concentration and the risk
of respiratory diseases has been well documented by epidemiological studies. However, the …