[图书][B] Defining the role of mechanical signals during nerve root compression in the development of sustained pain and neurophysiological correlates that develop in …
KJ Nicholson - 2013 - search.proquest.com
Cervical nerve root injury commonly leads to pain. The duration of an applied compression
has been shown to contribute to both the onset of persistent pain and also the degree of …
has been shown to contribute to both the onset of persistent pain and also the degree of …
Development of a duration threshold for modulating evoked neuronal responses after nerve root compression injury
KJ Nicholson, JC Quindlen, BA Winkelstein - 2011 - sae.org
Cervical nerve roots are susceptible to compression injuries of various durations. The
duration of an applied compression has been shown to contribute to both the onset of …
duration of an applied compression has been shown to contribute to both the onset of …
An in vivo model of transient cervical nerve root compression: Thresholds for mechanical allodynia and neuronal responses
RD Hubbard - 2008 - search.proquest.com
During axial loading or non-physiologic motions of the neck, the cervical nerve roots can
become transiently compressed by the surrounding bony structures of the intervertebral …
become transiently compressed by the surrounding bony structures of the intervertebral …
Cell-specific inflammatory spinal responses in cervical nerve root compression: Cellular reactivity and cytokines in pain
SM Rothman - 2009 - search.proquest.com
As many as 30% of Americans suffer from chronic pain. Both chemical irritation and
mechanical compression have been implicated in nerve root-mediated pain. However, the …
mechanical compression have been implicated in nerve root-mediated pain. However, the …
Transient nerve root compression load and duration differentially mediate behavioral sensitivity and associated spinal astrocyte activation and mGLuR5 expression
Injury to the cervical nerve roots is a common source of neck pain. Animal models of nerve
root compression have previously established the role of compression magnitude and …
root compression have previously established the role of compression magnitude and …
The roles of mechanical compression and chemical irritation in regulating spinal neuronal signaling in painful cervical nerve root injury
S Zhang, KJ Nicholson, JR Smith, TM Gilliland, PP Syré… - 2013 - sae.org
Both traumatic and slow-onset disc herniation can directly compress and/or chemically
irritate cervical nerve roots, and both types of root injury elicit pain in animal models of …
irritate cervical nerve roots, and both types of root injury elicit pain in animal models of …
Transient cervical nerve root compression modulates pain: load thresholds for allodynia and sustained changes in spinal neuropeptide expression
RD Hubbard, Z Chen, BA Winkelstein - Journal of biomechanics, 2008 - Elsevier
Nerve root compression produces chronic pain and altered spinal neuropeptide expression.
This study utilized controlled transient loading in a rat model of painful cervical nerve root …
This study utilized controlled transient loading in a rat model of painful cervical nerve root …
Riluzole effects on behavioral sensitivity and the development of axonal damage and spinal modifications that occur after painful nerve root compression
KJ Nicholson, S Zhang, TM Gilliland… - Journal of Neurosurgery …, 2014 - thejns.org
Object Cervical radiculopathy is often attributed to cervical nerve root injury, which induces
extensive degeneration and reduced axonal flow in primary afferents. Riluzole inhibits neuro …
extensive degeneration and reduced axonal flow in primary afferents. Riluzole inhibits neuro …
The Duration of a Nerve Root Compression Modulates Evoked Neuronal Responses in a Rat Model of Painful Injury
KJ Nicholson, BA Winkelstein - Summer …, 2011 - asmedigitalcollection.asme.org
The annual incidence for neck pain in the adult population is 30–50%[1]. The cervical nerve
roots are at risk for mechanical injury due to impingement of surrounding structures which …
roots are at risk for mechanical injury due to impingement of surrounding structures which …
Upregulation of GLT‐1 by treatment with ceftriaxone alleviates radicular pain by reducing spinal astrocyte activation and neuronal hyperexcitability
KJ Nicholson, TM Gilliland… - Journal of neuroscience …, 2014 - Wiley Online Library
Cervical nerve root injury commonly leads to radicular pain. Normal sensation relies on
regulation of extracellular glutamate in the spinal cord by glutamate transporters. The goal of …
regulation of extracellular glutamate in the spinal cord by glutamate transporters. The goal of …