Pseudomonas aeruginosa Alters Staphylococcus aureus Sensitivity to Vancomycin in a Biofilm Model of Cystic Fibrosis Infection

G Orazi, GA O'Toole - MBio, 2017 - Am Soc Microbiol
The airways of cystic fibrosis (CF) patients have thick mucus, which fosters chronic,
polymicrobial infections. Pseudomonas aeruginosa and Staphylococcus aureus are two of …

Pseudomonas aeruginosa Alginate Overproduction Promotes Coexistence with Staphylococcus aureus in a Model of Cystic Fibrosis Respiratory Infection

DH Limoli, GB Whitfield, T Kitao, ML Ivey, MR Davis Jr… - MBio, 2017 - Am Soc Microbiol
While complex intra-and interspecies microbial community dynamics are apparent during
chronic infections and likely alter patient health outcomes, our understanding of these …

Interspecific Small Molecule Interactions between Clinical Isolates of Pseudomonas aeruginosa and Staphylococcus aureus from Adult Cystic Fibrosis Patients

A Fugère, D Lalonde Séguin, G Mitchell, E Déziel… - PLoS …, 2014 - journals.plos.org
Pseudomonas aeruginosa and Staphylococcus aureus are the most prevalent pathogens in
airway infections of cystic fibrosis (CF) patients. We studied how these pathogens coexist …

Coculture of Staphylococcus aureus with Pseudomonas aeruginosa drives S. aureus towards fermentative metabolism and reduced viability in a cystic fibrosis model

LM Filkins, JA Graber, DG Olson, EL Dolben… - Journal of …, 2015 - Am Soc Microbiol
The airways of patients with cystic fibrosis are colonized with diverse bacterial communities
that change dynamically during pediatric years and early adulthood. Staphylococcus aureus …

[HTML][HTML] Maintenance of S. aureus in co-culture with P. aeruginosa while growing as biofilms

PW Woods, ZM Haynes, EG Mina… - Frontiers in …, 2019 - frontiersin.org
Bacterial biofilms are found in various environmental niches and are mostly comprised by
two or more bacterial species. One such example, are the mixed species bacterial biofilms …

Pseudomonas aeruginosa biofilm formation in the cystic fibrosis airway

S Moreau-Marquis, BA Stanton, GA O'Toole - Pulmonary pharmacology & …, 2008 - Elsevier
The cystic fibrosis (CF) lung is chronically inflamed and infected by Pseudomonas
aeruginosa, which is a major cause of morbidity and mortality in this genetic disease …

Use of artificial sputum medium to test antibiotic efficacy against Pseudomonas aeruginosa in conditions more relevant to the cystic fibrosis lung

S Kirchner, JL Fothergill, EA Wright, CE James… - JoVE (Journal of …, 2012 - jove.com
There is growing concern about the relevance of in vitro antimicrobial susceptibility tests
when applied to isolates of P. aeruginosa from cystic fibrosis (CF) patients. Existing methods …

Anaerobiosis influences virulence properties of Pseudomonas aeruginosa cystic fibrosis isolates and the interaction with Staphylococcus aureus

R Pallett, LJ Leslie, PA Lambert, I Milic, A Devitt… - Scientific reports, 2019 - nature.com
The airways of individuals with cystic fibrosis (CF) are abundantly colonised by
Staphylococcus aureus and Pseudomonas aeruginosa. Co-infecting hypoxic regions of …

Pseudomonas aeruginosa hypoxic or anaerobic biofilm infections within cystic fibrosis airways

DJ Hassett, MD Sutton, MJ Schurr, AB Herr… - Trends in …, 2009 - cell.com
The airways of patients afflicted with cystic fibrosis (CF) are colonized by many pathogens,
the most predominant of which is the Gram-negative bacterium Pseudomonas aeruginosa …

Staphylococcus aureus interaction with Pseudomonas aeruginosa biofilm enhances tobramycin resistance

T Beaudoin, YCW Yau, PJ Stapleton, Y Gong… - NPJ biofilms and …, 2017 - nature.com
Antimicrobial resistance is a significant threat to the treatment of infectious disease. Multiple
mechanisms of resistance to different classes of antibiotics have been identified and well …