It is clear from the preceding overview of histamine receptor pharmacology that research into
the pharmacology of histamine receptors is at an exciting stage of development. The rapid …

To evaluate the role of G‐protein‐coupled receptor kinases (GRK) in the desensitization of
the histamine H2 receptor, the H2 receptor was transiently cotransfected with GRK2, 3, 5 or …

7TMRs (seven-transmembrane receptors) exist as conformational collections in which
different conformations would lead to differential downstream behaviours such as receptor …

Presynaptic H3 receptors occur on histaminergic neurones of the CNS (autoreceptors) and
on non‐histaminergic neurones of the central and autonomic nervous system …

We have investigated the presence of histamine H3 receptors (H3Rs) on rat thalamic
isolated nerve terminals (synaptosomes) and the effect of their activation on glutamate and …

Since the cloning of the histamine H3 receptor cDNA in 1999 by Lovenberg and co-workers,
this histamine receptor has gained the interest of many pharmaceutical companies as a …

We report the discovery, tissue distribution and pharmacological characterization of a novel
receptor, which we have named H4. Like the three histamine receptors reported previously …

The pharmacology of histamine H3 receptors suggests the presence of distinct receptor
isoforms or subtypes. We herein describe multiple, functionally distinct, alternatively spliced …

The human histamine H4-receptor (hH4R) is expressed in mast cells and eosinophils and
mediates histamine (HA)-induced chemotaxis via Gi-proteins. For a detailed investigation of …

To examine the role of the C terminal tail in H2 receptor regulation, three cDNAs, encoding
truncated histamine H2 receptor mutants (H2T295, H2T307, and H2T341), were constructed …