Simple Summary Ca2+ dyshomeostasis is implicated in several key pathophysiological
processes attributed to cancer metastasis biology. Here, we decipher the role of intracellular …

Metastasis is still the primary cause of cancer-related mortality. However, the underlying
mechanisms of cancer metastasis are not yet fully understood. Currently, the epithelial …

Ca 2+ is a ubiquitous and dynamic second messenger molecule that is induced by many
factors including receptor activation, environmental factors, and voltage, leading to …

Abstract Intracellular calcium (Ca2+) signals are key regulators of multiple cellular functions,
both healthy and physiopathological. It is therefore unsurprising that several cancers present …

Highlights•Altered Ca 2+ homeostasis is a hallmark of cancer cells.•Deregulation of cytosolic
[Ca 2+] is implicated in metastasis and apoptosis-resistance.•Genes involved in cancer …

Background Although the study of calcium (Ca 2+) is classically associated with excitable
cells such as myocytes or neurons, the ubiquity of this essential element in all cellular …

Introduction: Cancer is caused by defects in the mechanisms underlying cell proliferation,
death and migration. Calcium ions are central to all of these phenomena, serving as major …

Cancer is caused by excessive cell proliferation and a propensity to avoid cell death, while
the spread of cancer is facilitated by enhanced cellular migration, invasion, and …

Cancer involves defects in the mechanisms underlying cell proliferation, death and
migration. Calcium ions are central to these phenomena, serving as major signalling agents …

Intracellular Ca 2+ ions that are thought to be one of the most important second messengers
for cellular signaling, have a substantial diversity of roles in regulating a plethora of …