Deciphering the Role of Ca2+ Signalling in Cancer Metastasis: From the Bench to the Bedside
Simple Summary Ca2+ dyshomeostasis is implicated in several key pathophysiological
processes attributed to cancer metastasis biology. Here, we decipher the role of intracellular …
processes attributed to cancer metastasis biology. Here, we decipher the role of intracellular …
[HTML][HTML] Advances in the study of cancer metastasis and calcium signaling as potential therapeutic targets
C Cui, Y Zhang, G Liu, S Zhang, J Zhang… - Exploration of Targeted …, 2021 - ncbi.nlm.nih.gov
Metastasis is still the primary cause of cancer-related mortality. However, the underlying
mechanisms of cancer metastasis are not yet fully understood. Currently, the epithelial …
mechanisms of cancer metastasis are not yet fully understood. Currently, the epithelial …
Ca2+ as a therapeutic target in cancer
S Gross, P Mallu, H Joshi, B Schultz, C Go… - Advances in cancer …, 2020 - Elsevier
Ca 2+ is a ubiquitous and dynamic second messenger molecule that is induced by many
factors including receptor activation, environmental factors, and voltage, leading to …
factors including receptor activation, environmental factors, and voltage, leading to …
Molecular mechanisms of tumour invasion: Regulation by calcium signals
O Iamshanova, A Fiorio Pla… - The Journal of …, 2017 - Wiley Online Library
Abstract Intracellular calcium (Ca2+) signals are key regulators of multiple cellular functions,
both healthy and physiopathological. It is therefore unsurprising that several cancers present …
both healthy and physiopathological. It is therefore unsurprising that several cancers present …
Alterations of calcium homeostasis in cancer cells
S Marchi, P Pinton - Current opinion in pharmacology, 2016 - Elsevier
Highlights•Altered Ca 2+ homeostasis is a hallmark of cancer cells.•Deregulation of cytosolic
[Ca 2+] is implicated in metastasis and apoptosis-resistance.•Genes involved in cancer …
[Ca 2+] is implicated in metastasis and apoptosis-resistance.•Genes involved in cancer …
A temporal examination of calcium signaling in cancer-from tumorigenesis, to immune evasion, and metastasis
Background Although the study of calcium (Ca 2+) is classically associated with excitable
cells such as myocytes or neurons, the ubiquity of this essential element in all cellular …
cells such as myocytes or neurons, the ubiquity of this essential element in all cellular …
Targeting Ca2+ transport in cancer: close reality or long perspective?
N Prevarskaya, R Skryma, Y Shuba - Expert opinion on therapeutic …, 2013 - Taylor & Francis
Introduction: Cancer is caused by defects in the mechanisms underlying cell proliferation,
death and migration. Calcium ions are central to all of these phenomena, serving as major …
death and migration. Calcium ions are central to all of these phenomena, serving as major …
Targeting the calcium signalling machinery in cancer
JIE Bruce, AD James - Cancers, 2020 - mdpi.com
Cancer is caused by excessive cell proliferation and a propensity to avoid cell death, while
the spread of cancer is facilitated by enhanced cellular migration, invasion, and …
the spread of cancer is facilitated by enhanced cellular migration, invasion, and …
Remodelling of Ca2+ transport in cancer: how it contributes to cancer hallmarks?
N Prevarskaya, H Ouadid-Ahidouch… - … of the Royal …, 2014 - royalsocietypublishing.org
Cancer involves defects in the mechanisms underlying cell proliferation, death and
migration. Calcium ions are central to these phenomena, serving as major signalling agents …
migration. Calcium ions are central to these phenomena, serving as major signalling agents …
[HTML][HTML] Overview of Ca2+ signaling in lung cancer progression and metastatic lung cancer with bone metastasis
MT Tran - Exploration of Targeted Anti-tumor Therapy, 2021 - ncbi.nlm.nih.gov
Intracellular Ca 2+ ions that are thought to be one of the most important second messengers
for cellular signaling, have a substantial diversity of roles in regulating a plethora of …
for cellular signaling, have a substantial diversity of roles in regulating a plethora of …