Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: multicentre randomised trial
PD Gluckman, JS Wyatt, D Azzopardi, R Ballard… - The Lancet, 2005 - thelancet.com
Background Cerebral hypothermia can improve outcome of experimental perinatal hypoxia-
ischaemia. We did a multicentre randomised controlled trial to find out if delayed head …
ischaemia. We did a multicentre randomised controlled trial to find out if delayed head …
Assessment of brain tissue injury after moderate hypothermia in neonates with hypoxic–ischaemic encephalopathy: a nested substudy of a randomised controlled trial
Background Moderate hypothermia in neonates with hypoxic–ischaemic encephalopathy
might improve survival and neurological outcomes at up to 18 months of age, although …
might improve survival and neurological outcomes at up to 18 months of age, although …
Neurological outcomes at 18 months of age after moderate hypothermia for perinatal hypoxic ischaemic encephalopathy: synthesis and meta-analysis of trial data
Objective To determine whether moderate hypothermia after hypoxic-ischaemic
encephalopathy in neonates improves survival and neurological outcome at 18 months of …
encephalopathy in neonates improves survival and neurological outcome at 18 months of …
Neurodevelopmental outcome of infants treated with head cooling and mild hypothermia after perinatal asphyxia
MR Battin, JA Dezoete, TR Gunn, PD Gluckman… - …, 2001 - publications.aap.org
Objectives. To determine the neurodevelopmental outcome of infants treated with head
cooling with systemic hypothermia after hypoxic-ischemic encephalopathy. Study Group …
cooling with systemic hypothermia after hypoxic-ischemic encephalopathy. Study Group …
Therapeutic hypothermia for hypoxic–ischaemic encephalopathy in the newborn infant
M Thoresen, A Whitelaw - Current opinion in neurology, 2005 - journals.lww.com
In term infants with HIE there is emerging evidence that both selective head cooling and
whole body cooling are neuroprotective and safe. This is consistent with a wealth of …
whole body cooling are neuroprotective and safe. This is consistent with a wealth of …
A systematic review of cooling for neuroprotection in neonates with hypoxic ischemic encephalopathy–are we there yet?
SM Schulzke, S Rao, SK Patole - BMC pediatrics, 2007 - Springer
Background The objective of this study was to systematically review randomized trials
assessing therapeutic hypothermia as a treatment for term neonates with hypoxic ischemic …
assessing therapeutic hypothermia as a treatment for term neonates with hypoxic ischemic …
Determinants of outcomes after head cooling for neonatal encephalopathy
JS Wyatt, PD Gluckman, PY Liu, D Azzopardi… - …, 2007 - publications.aap.org
OBJECTIVE. The goal of this study was to evaluate the role of factors that may determine the
efficacy of treatment with delayed head cooling and mild systemic hypothermia for neonatal …
efficacy of treatment with delayed head cooling and mild systemic hypothermia for neonatal …
Cooling for newborns with hypoxic ischaemic encephalopathy
SE Jacobs, M Berg, R Hunt… - Cochrane database …, 2013 - cochranelibrary.com
Background Newborn animal studies and pilot studies in humans suggest that mild
hypothermia following peripartum hypoxia‐ischaemia in newborn infants may reduce …
hypothermia following peripartum hypoxia‐ischaemia in newborn infants may reduce …
Effect of therapeutic hypothermia initiated after 6 hours of age on death or disability among newborns with hypoxic-ischemic encephalopathy: a randomized clinical …
AR Laptook, S Shankaran, JE Tyson, B Munoz, EF Bell… - Jama, 2017 - jamanetwork.com
Importance Hypothermia initiated at less than 6 hours after birth reduces death or disability
for infants with hypoxic-ischemic encephalopathy at 36 weeks' or later gestation. To our …
for infants with hypoxic-ischemic encephalopathy at 36 weeks' or later gestation. To our …
Childhood outcomes after hypothermia for neonatal encephalopathy
S Shankaran, A Pappas, SA McDonald… - … England Journal of …, 2012 - Mass Medical Soc
Background We previously reported early results of a randomized trial of whole-body
hypothermia for neonatal hypoxic–ischemic encephalopathy showing a significant reduction …
hypothermia for neonatal hypoxic–ischemic encephalopathy showing a significant reduction …
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