Regenerative engineering strategies for the oral mucoperiosteum, as may be needed
following surgeries, such as cleft palate repair and tumor resection, are underdeveloped …

Many conditions, including cancer, trauma, and congenital anomalies, can damage the oral
mucosa. Multiple cultures of oral mucosal cells have been used for biocompatibility tests and …

Tissue-engineered oral mucosa, in the form of epithelial cell sheets or full-thickness oral
mucosa equivalents, is a potential solution for many patients with congenital defects or with …

Objectives Severe oral mucosal and tissue defects can lead to pain, infection, and later
undesirable healing of scarring and adhesion, resulting in a poor quality of life. In vitro …

The large defect of oral and maxillofacial region doesn't only affect the function and
aesthetics but also has an adverse impact on patients' psychology. The traditional way to …

Cleft lip and palate (CL/P) is the most prevalent craniofacial birth defect in humans. None of
the surgical procedures currently used for CL/P repair lead to definitive correction of hard …

Traditional methods of repair for medium-size (3–5 cm) oral defects include allowing
granulation, primary closure, skin grafts, and buccal mucosal grafts. Each of these methods …

The use of mucoperiostial flaps during cleft palate surgery is associated with altered palatal
bone growth and development. We analyzed the potential usefulness of a bioengineered …

Many types of soft tissue grafts have been used for the reconstruction of oral mucosal
defects. The best results are achieved with mucosal grafts; however, when large areas must …

Within the last decade a new field of 'tissue engineering'or 'regenerative medicine'has
emerged that offers a new and exciting alternative for soft tissue reconstruction. This review …