Abstract Purpose of Review Anxiety-and trauma-related disorders are prevalent and
debilitating mental illnesses associated with a significant socioeconomic burden. Current …

The endocannabinoid system has recently emerged as a promising therapeutic target for the
treatment of stress-related emotional disorders. A growing literature base has collectively …

Repeated stress is one of the environmental factors that precipitates and exacerbates
mental illnesses like depression and anxiety as well as cognitive impairments. We have …

Endogenous cannabinoids play an important role in the physiology and behavioral
expression of stress responses. Activation of the hypothalamic–pituitary–adrenal (HPA) axis …

Most psychiatric disorders are characterized by emotional memory or learning disturbances.
Chronic mild stress (CMS) is a common animal model for stress-induced depression. Here …

The endocannabinoid (eCB) system has attracted attention for its role in various behavioral
and brain functions, and as a therapeutic target in neuropsychiatric disease states, including …

Background: There is a growing liberalization of cannabis-based preparations for medical
and recreational use. In multiple instances, anxiety and depression are cited as either a …

The central endocannabinoid system is a neuroactive lipid signalling system in the brain
which acts to control neurotransmitter release. The expression patterns of this system …

The endogenous cannabinoid system is an important regulatory system involved in
physiological homeostasis. Endocannabinoid signaling is known to modulate neural …

Two topics are presented in this review. In the first section, we review data regarding the
effects of the endocannabinoids (eCBs) and cannabinoid receptors on neuroimmune …